Quantitative Study Of Aortic Root Anatomic Structure By 256iCT

Part1 Quantitative study of aortic root dimension changes duringcardiac cycle by 256 i CTObjective: The aim of this study was to disscuss the changes in aortic r- oot dimensions during systole and diastole with ECG-gated multidetector row computed tomography(MDCT).Methods: 150 patients with normal 256 i CT coronary artery CTA results were collected.Retrospectively, ECG-gated reconstructions at each 10% of the cardiac cycle were made and analyzed during systole(30%) and diastole(70%). Axial planes were reconstructed at three different levels of the aortic root(AV annulus, sinuses of Valsalva and STJ). At each level the maximal and the minimal diameters were measured and analyzed the changes during the systole and diastole.Results:1There was a significant difference between the systole and diastole,The diameters,both Dmax and Dmin, were significantly larger than the diameters of the diastole aortic root;2No significant correlation was found between changes in neither of aortic root dimensions during cardiac cycle and patients’ age.3There was a significant difference between the male and female’s diameters. The diameters, both Dmax and Dmin,were significantly larger than the diameters of the female aortic root(P<0.05),both Dmax and Dmin had some difference between males and females in Aortic annulus level and Sinus tube junction level according standardization heights and weights(P<0.05).4During the 30% interval and 70% interval, we Proposed the 95% confidence interval in three levels of the aortic root dimensions.Conclusion:The aortic root anatomy demonstrated a high inter-individualvariability and cardiac cycle dependency.The dynamic morphological study o-f the aortic root based on the cardiac cycle might support the selection and assess of cardiothoracic surgeons in their prosthesis design. Part2 Quantitative study of the adjacent structures of aortic root by256i CTObjective: The aim of this study was using 256 slice coronary CTA to measure the adjacent structures of aortic root quantitatively, Putting forward the normal reference value range, and discussing its relativity with gender.Method: The normal measured Imaging data of 150 patients with 256 i CT coronary artery CTA were collected retrospectively. Including Male 73 cases, female 77 cases, and the mean age was(51.3+12.4).Then we used Cardiac function analysis software and Recombinant technology measured the height of left and right coronary sinus mouth ipsilateral and the Lateral offset value with The inner diameter of the aortic annulus during the systole(30%) and diastole(70%).While we analyzed the variation between the systolic and diastolic with one-way ANOVA.Result: 1There are significant differences in systolic and diastolic of LCO and the value of the Right Lateral shift(LSC) of the coronary ostia to the inner border of the aortic annulus(P<0.05).no significant differences between others(P>0.05); 2There were significant differences between men and women with LCO and RCO(P<0.05); the values of Left and Right coronary mouth laterally offset aortic annulus bore were no significant differences during male and female(P>0.05).Even the values were standardized according to body surface area(P<0.05).3We proposed the 95% confidence interval of RCO/LCO and the Left and Right coronary mouth laterally offset aortic annulus bore.Conclusion: Aortic root adjacent structures have significant inter-individual variability and cardiac cycle–dependence. The reference range provides strong support for the selection, design and evaluation during valve replacement surgery. Part3 Comparison of aortic root anatomic structure and left heartfunction between the patients with and without hypertensionusing 256 i CTObjective:The aim of this study was to disscuss the changes in aortic root dimensions during cardiac cycle and left heart function between the patients with and without hypertension using 256 i CT.Methods: 44 cases of hypertensive patients were selected for the study group, 44 cases of healthy patients as a control group. The 256 i CT coronary artery CTA results of all patients and normal people were collected. Axial planes were reconstructed at three different levels of the aortic root(AV annulus, sinuses of Valsalva and STJ). At each level the maximal and the minimal diameters were measured and the changes during the systole and diastole were analyzed. The measured data were statistically analyzed.Results:1There was no significant difference between the hypertensive patients and healthy patients’ diameters during the systole and diastole(P>0.05).2Comparison of the left heart function between the patients with hypertension and healthy patients,There were significant different in EF and CO and MM(P<0.05). No significant differences between other groups(P>0.05).Conclusion: 256 i CT can objective evaluate the difference of aortic root anatomic structure and left heart function between the hypertensive patients.