211 Cases Of Post Infection Cough In Beijing TCM Syndrome Distribution Investigation And Pathogenesis Research Specialty:Internal Medicine Of TCM

BackgroundPost-infection cough (CPI) is a clinically frequently encountered disease, the domestic and foreign research findings of post infection cough accounted for etiology of chronic cough in the 8%-3O% range.Post-infection cough disease incidence rate is high, refractory protracted illness, serious impact on the work and life of patients. Since the 2009 edition of "guide for diagnosis and treatment of cough" definition of the disease, we gradually understand and concern, sought for the rapid and effective treatment of this disease appears especially urgent.In recent years, traditional Chinese medicine treatment of the disease curative effect reflects the traditional Chinese medicine in the treatment of post-infection advantage. The etiology and pathogenesis of post-infection cough belongs to the experience of TCM, most post-infection cough type has a certain randomness.TCMsyndrome diagnosis standard according to the experience of self understanding, or by reference to a standard knowledge transformation experience combines, demonstration research and clinical expert system lack of a large sample of syndrome the diagnosis of disease, diagnosis, syndrome of post-infection cough isvague.Therefore, a correct understanding of the syndrome is the premise of traditional Chinese medicine has curative effect, carry out epidemiological study on TCM syndromes, diagnosis, and based on the specification of TCM syndrome of definite pathogenesis is the premise for developing TCM treatment scheme.ObjectiveThesurvey was conducted in patients with post-infection cough, through statistical analysis, the distribution of TCM Syndromes of post-infection cough. At the same time as the next step to carry out a large sample, multi center post-infection cough and laying the foundation of curative efficacy and prescription research and the diagnosis and treatment of traditional Chinese medicine.MethodThrough literature research and expert consultation, reference pre survey feedback information results, four diagnostic information of questionnaire design and the formation of post infection cough, symptoms and signs on the investigation to the clinic 211 patients who accorded with the diagnostic standard in 2014 April-2014 December, by the investigators write four diagnostic information table. The Epidata 3.1 software to establish database using data collected by the statistical method, and then use SPSS 17.0 statistical software for Logistic regression etc., and preliminary analysis of distribution features of TCM Syndromes of inductive post infection cough and various types of syndromes of primary and secondary disease composition, in order to confirm the basic syndrome and corresponding diagnostic criteria.Result:211 cases of post-infection cough,by the cluster analysis, The TCM Syndrome Differentiation for syndrome type 4, respectively, of lung heat consume yin syndrome, wind-qi poly pharynx syndrome, liver and lung dysfunction syndrome, syndrome of obstruction of lung qi, and the type of distribution and the primary and secondary, in carries on the discussion, the obstruction of lung qi and lung and liver dysfunction syndrome is most common, were 78 cases and in 68 cases, accounted for 37% and 32.2%; and lung heat consume yin syndrome and wind-qi poly pharynx syndrome are more common, respectively 48 cases and 17 cases, respectively,accounting for 22.7% and 8.1%. That post- infection cough was the main cause of external evil invasion of the body, loss of treatment, or long duration, caused by residual pathogen, Lead to stagnation of Qi, liver and lung dysfunction, purifying and descending function of the lung, the adverse-rising of qi, Inverse gas induced cough; Stagnation of Qi change into the fire or impairment of yin; or evil Qi disturbance in the pharynx, throat itching, cough induced by cold air stimulation.The symptom is composed of the following:1 lung heat consume yin syndrome:main symptoms:cough, hoarseness, sore throat and pharyngeal foreign body sensation;secondary symptoms, sputum amount, thick phlegm, phlegm, bitter taste in the mouth, bosom frowsty,thirsty to drink.2 wind-qi poly pharynx syndrome:main symptoms:paroxysmal cough, throat itching, cough.Secondary symptoms:cold air stimulation induced cough, cough induced by tobacco smoke, smoke flavor induced cough, the cough induced by emotional factors, posture change induced cough, the cough induced by over fatigue, cold cough, white sputum, thick phlegm.3 liver and lung dysfunction syndrome:main symptoms:dry cough, cough cited loud, pain in chest and hypochondrium; secondary symptoms:cough aggravating since morning, increased fatigue, less sputum, sputum white, thick sputum, thirst.4 syndrome of obstruction of lung qi:main symptoms:cough sound short, dry throat, cough without significant time difference; secondary symptoms:cough, sputum amount, thick sputum, thirst, loss of appetite.ConclusionTCM Syndromes of post-infection cough are lung heat consume yin syndrome, wind-qi poly pharynx syndrome, liver and lung dysfunction syndrome, syndrome of obstruction of lung qi. The obstruction of lung qi and lung and liver dysfunction syndrome is most common; and lung heat consume yin syndrome and wind-qi poly pharynx syndrome are more common. That post- infection cough was the main cause of external evil invasion of the body, loss of treatment, or long duration, caused by residual pathogen, Lead to stagnation of Qi, liver and lung dysfunction, purifying and descending function of the lung, the adverse-rising of qi, Inverse gas induced cough; Stagnation of Qi change into the fire or impairment of yin; or evil Qi disturbance in the pharynx, throat itching, cough induced by cold air stimulation.The distribution of TCM syndromes in this study is helpful to the next step of research and the curative effect of TCM diagnosis and treatment.