Study Of Integrated Visual And Auditory Continuous Performance Test In Asthmatic Children

Objectives:The aim of this study was to evaluate the characteristics of control response and sustained attention in children with asthma by using the IVA-CPT software, and to explore the relationship between the asthma in different control level and their attention.Methods:The study involved a random population of 90 asthmatic children (aged from 6 to 11 years) from pediatrics in the people’s Hospital of Guangxi Zhuang Autonomous Region. According to the levels of asthma treatment (controlled、partly controlled、uncontrolled), the asthmatic group were divided into three subgroups, and 45 healthy children as control group whose age, sex and the level of education were similar to asthmatics. All parents of asthmatic children would be completed the clinical questionnaire that associated with asthma by using the method of one to one that is a asthma specialist directed the patient of asthma on-site. The parameters of lung function in asthmatic children were measured by using Jaeger Master Screen diffusion determinator. At the same time all individuals were assessed control response and sustained attention by the Nanjing wei medical technology Company IVA-CPT software. The results of IVA-CPT including FSAQ, VAQ and AAQ were compared between asthmatic children and control group.Results:1. The means of FSAQ and AAQ in the children with asthma were lower than those in control group; The means of VAQ,VIG-V, VIG-A, SPE-V and SPE-A were significantly lower than those in control group (p<0.01).All the response quotient had no significant difference between asthmatic group and control group. (p>0.05).2. The abnormal rates of attention indexes in children with asthma:FSAQ (33.33%),AAQ (31.11%),VAQ (34.44%),VIG-A (34.44%),VIG-V (36.67%),FOC-A (28.89%),FOC-V (28.89%),SPE-A (20%) and SPE-V (24.44%). The abnormal rates of VAQ and SPE-A were higher than that of the healthy children (P<0.05); The results also indicated that there was a significant difference in VIG-A,VIG-V and SPE-V (P<0.01);The abnormal rates of FSAQ, AAQ, FOC-V and FOC-A had no significant difference between the asthma group and control group. (p>0.05).3. There was significant difference among these three groups(controlled group、partly controlled group、uncontrolled group) in the means of FSAQ,VAQ and AAQ.The means of FSAQ,VAQ and AAQ had no statistical significant between uncontrolled group and partly controlled group (p>0.05).The uncontrolled group scored significantly lower than children with well controlled asthma in the means of FSAQ, VAQ and AAQ (p<0.05).The means of VAQ was significantly lower in children with partly controlled asthma compared with well controlled group(p<0.05). There were no statistical differences in means of FSAQ and AAQ between the partly controlled asthmatic children and the well controlled group (p>0.05).4. The means of FSAQ,VAQ and AAQ in children with uncontrolled asthma were significantly lower than those in control group(p<0.01).5. The means of FSAQ and VAQ in children with partly controlled asthma were significantly lower than those in control group(p<0.05),The means of AAQ had no significant difference in children with partly controlled asthma compared to control group (p>0.05).6.The means of FSAQ,VAQ and AAQ had no significant difference in children with well controlled asthma compared to control group (p>0.05). Conclusions:1. There was sustained attention damage in children with asthma, particularly the ability of keeping visual attention.2. The degree of attention damage in asthmatic children would be associated with the level of asthma control.