Compliance And Influencing Factors Of Antiplatelet Therapy In Patients With Coronaiy Heart Disease One Year After Hospitalization

Objective To analyze the compliance of antiplatelet therapy and its influencing factors in patients with coronary heart disease one year after hospitalization, so that an improvement will be made on the secondary prevention for coronary heart disease. Methods By cross-sectional investigation, the study enrolled 398 patients with first-diagnosed coronary heart disease in a certain grade-3 A hospital in Anhui Province from January to December 2012, and 363 of them completed the study at last. The therapeutic compliance of these patients, as well as the influencing factors, was evaluated with a self-designed questionnaire through either out-patient interview or phone revisit. The factors influencing therapeutic compliance of patients with coronary heart disease were analyzed with logistic regression analysis. Results The results showed that 301 patients(83%,301/363) were in a good therapeutic compliance, while the rest of 62 patients(17%,62/363) were not. The reasons of drug with drawal: arbitrary decisions being 38 cases(61%,38/62), the doctor’s advices 14 cases(23%,14/62), the economic dilemma 7 cases(11%,7/62), and adverse drug reaction 3 cases(5%,3/62). Simple factor analysis displays that ways of medical payment(P=0.044,c2=6.262), the condition whether with PCI treatment or not(P=0.018,c2=5.556), and the different groups of coronary heart disease(stable angina pectoris,unstable angina pectoris and acute myocardial infarction)(P=0.032, c2=6.895)were related to the compliance of antiplatelet therapy. The main influencing factors were the age[OR=0.471(0.284~0.782)] and the condition whether with PCI therapy or not [OR=2.104(1.123~3.942)]. Conclusions Patients with coronary heart disease had noncompliance in antiplatelet therapy one year after hospitalization. Therefore, medical staff should make treatment protocol and take nursing measures according to age, condition whether with PCI treatment or not, ways of medical payment and the different groups of coronary heart disease so that the medication compliance can be elevated and the secondary prevention well implemented.