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Influence Analysis Of Hepatic Steatosis To Infection After Liver Resection And Other Complications

Posted on:2015-11-22Degree:MasterType:Thesis
Country:ChinaCandidate:X H WangFull Text:PDF
GTID:2284330461998729Subject:Surgery
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Objective: To study the effect on the analysis of liver fatty degeneration of liver resection of postoperative complications such as infection, and provide guidance for the clinical prevention of infection.Methods: retrospective analysis of the first, Second Affiliated Hospital of Medical University Of Anhui from November to 2013 in 2010 November admitted to the Department of general surgery with liver fatty degeneration of liver cancer received liver resection in 78 cases of the disease, as the observation group, the other from the same period in our hospital from liver cancer received liver resection of non hepatic steatosis in patients with hepatocellular carcinoma in 78 cases, as a control group. The clinical data from two groups of patients, including sex, age, body mass index, diabetes, hepatitis and cirrhosis of the liver, operation mode and the scope of consolidation, operation complications and mortality, compared two groups of patients with postoperative complications and death occurred, the complications are divided into mild and severe complications, and tumor necrosis factor of two groups after surgery(TNF-α), interleukin 1β(IL-β1), interleukin- 6(IL-6)werecompared.Results: the two groups in age, gender, operation mode and the patients inthe observation group the postoperative infection complication rate was 71.79%, significantly higher than that in control group 52.56%, grade 2 and grade 3 infection patients in the observation group patients cases were 30 cases and 9 cases, significantly more than the control group of 16 cases and in 2 cases, patients in the observation group after operation was 157.91 + 28.33 pg/m L TNF-α, IL-1 βas 99.46 + 23.38 pg/m L, IL-6 level was 49.12 + 11.29pg/m L, are significantly higher than before treatment, 77.93 + 19.47 pg/m L, 73.60 + 17.32pg/m L, 15.18 + 6.85pg/m L and control group after treatment of 128.32 + 25.2, 87.61 + pg/m L 20.24pg/m L, 26.18 + 9.57pg/m L, patients in the observation group postoperative prealbumin level was 0.10 + 0.03 pg/m L, significantly lower than that before treatment and 0.25 + 0.06 pg/m L, and the control group after treatment of 0.15 + 0.05 pg/m L, with significant difference.Conclusion: hepatic steatosis increased liver resection after infection complication rate, inthe clinical course of treatment, need special attention.
Keywords/Search Tags:liver fatty degeneration, liver resection, infection, complication
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