Based On Analysis Of Metabonomics Research Malignant Tumor Kidney Depletion-phlegm-stasis Syndrome And Uygur Medicine Abnormal Savda Syndrome

Objective:Analysis of abnormal savda munziq intervention of Kidney Depletion-phlegm-stasis syndrome compared before and after the patient’s own blood plasma of healthy crowd, nuclear magnetic resonance hydrogen spectrum metabolomics differences that abnormal savda type and kidney phlegm and blood stasis of TCM syndrome is a common pathological body physiological changes of different medical theory in this paper.Methods:According to the inclusion criteria to collection Kidney Depletion-phlegm-stasis syndrome and blood stasis syndrome in patients with cancer of abnormal savda intervention munziq and the health control group before and after the plasma itself,with ’H-NMR based metabonomics,the data is analyzed by Orthogonal Partial Least-Squares Discriminant Analysis (OPLS-DA),Studies of healthy people with Kidney Depletion-phlegm-stasis syndrome in patients with cancer metabolism of plasma group differences before and after medication.Results:group C in patients with plasma amino acids such as branched chain amino acid, such as glutamic acid, lactic acid, glycoprotein and relatively increased, inositol and alanine,1-methyl histidine, glutamine, VLDL, glucose, creatine and shark inositol is group H reduce; C Group vs M group:M group in patients with plasma glycine, alanine, glutamine, glucose and VLDL higher than group C, isoleucine, glutamic acid, acetylcysteine, lactic acid, glycoprotein, and 1-methyl histidine, leucine, valine, creatine, shark inositol and inositol in before and after treatment had no obvious difference; H Group vs M group:M group in patients with plasma isoleucine, glutamine,1-methyl histidine, glucose, VLDL, creatine and shark inositol is a healthy person is high, leucine, valine, glutamic acid, glycine, acetylcysteine, alanine, lactic acid, glycoprotein and inositol relatively low group H.Conclusion:Kidney Depletion-phlegm-stasis syndrome tumor patients of phlegm stasis syndrome involves the sugar, amino acid, fat and energy metabolism and other metabolic disorders; abnormal savda munziq may by adjusting the metabolic pathway effects on Kidney Depletion-phlegm-stasis syndrome phlegm and blood stasis syndrome in patients with cancer; According to the different disease with syndrome, with certificate in the same way, similarly tongfang tongfang stagnation "theory, and" the condition combination, the corresponding "principle, in the opposite, is speculated that uygur abnormalities black bile, and kidney deficiency of TCM phlegm stasis may exist the micro contact and the common material basis, is a common pathological body physiological changes of different medical theory.