Ultrasound Elastography Area Ratio And Improved Score Of Breast Differential Diagnosis Of Benign And Malignant

Objective:1. To be measured breast lesions of gray elastic graph chart area, calculatingits area ratio, using the ratio of the area to determine the probability of malignant breasttumors predicted values, drawing ROC curve, using the area ratio of the area under thecurve to determine whether there is clinical diagnostic value. At the same time, we canaccept the best diagnostic point to diagnose the benign and malignant breast lesions,providing another useful indicator of ultrasound elastography to diagnose benign andmalignant breast lesions.2. To be used the area ratio of ultrasound elastography andscore as the method of benign and malignant breast lumps identification.Methods: Examination of89patients with a total of100cases of breast tumor lesionswith two-dimensional ultrasound and ultrasound elastography, obtaining the satisfactionof both images, using the5-point improvement points method as the diagnosticreference standard score, measuring the lesion area and the two-dimensional elasticimage area, and calculating its area ratio, taking pathological results as the gold standard,plotting the ROC curve, having optimum diagnostic cutoff point of differentiatingbenign and malignant tumors, and then using the critical point and the Itoh5pointsmethods to diagnose the benign and malignant tumors, comparing its value, sensitivity,specificity and accuracy.Results:1. Difference between elastography map and the area ratio of thetwo-dimensional gray-scale sonography of benign and malignant breast lumps had statistically significant (P≤0.01), using the probability area ratio of the predicted valueof ultrasound elastography to construct the ROC curve, area under the curve was0.976,when the critical point of diagnosis was1.27, the sensitivity, specificity and accuracywere90.16%,85.00%and89.00%, separately. And malignant nodules area ratio wassignificantly higher than benign nodules.2. Diagnostic ultrasound elastographyhardness rating of benign and malignant breast tumor sensitivity, specificity andaccuracy were86.89%,80.00%and87.00%, comparing with diagnostic ultrasoundelastography area ratio in line with the rate was not statistically significant (P≥0.05)Conclusions:1. Ultrasound elastography area ratio can be indirectly reflected breastlumps scope and extent of the surrounding tissue involvement, is more flexible,objective quantitative of analysis elasticity image than imaging hardness score. As so as,ultrasound elastography area ratio can be measured as another useful indicator of theidentification of benign and malignant breast lumps, such as when the area ratio of1.27is the best diagnostic point, there is a better diagnostic value.2. Ultrasound elastographytechnique can be examined tumor response hardness information, the accuracy of it ismore higher than high-frequency ultrasound, can help diagnosing difficult differentialdiagnosis of benign and malignant breast lesions of color Doppler ultrasound. In clinical,combining with elastography area ratio can be to improve the accuracy of diagnosis ofbreast cancer, reducing the rate of misdiagnosis.