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Risk Factors And Treatment Strategy Of Restenosis After PCI Stenting In Patients With Coronary Artery Disease

Posted on:2016-05-01Degree:MasterType:Thesis
Country:ChinaCandidate:B DuFull Text:PDF
GTID:2284330467499153Subject:Internal medicine
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Objective: To investigate the risk factors of restenosis after coronarystenting in patients with coronary artery disease PCI and its treatmentstrategy.Methods: randomly selected in January2012-2014years1monthto the first hospital of Jilin University diagnosed coronary heart diseaseand undergoing coronary stenting and within12-14months of827patients with angiographic follow-up. Aged30-89years, including582males and245females. According to coronary angiography follow-upresults, which is divided into no restenosis group and restenosis group,which non restenosis group of698cases,488cases male,210cases offemale, restenosis group (129cases),94cases of male,35were female.There were51cases of restenosis patients in the6-8months aftercoronary angiography again, of which,15cases of simple balloondilatation,36cases of stent implantation. The clinical data, biochemicalresults and surgical data of the patients were collected and statisticallycollected.. Using multivariate logistic regression analysis of clinicalfeatures and coronary angiographic characteristics and surgical operationand in stent restenosis correlation using χ2test analysis in stent restenosisdifferent treatment strategies (simple balloon dilatation and stentingrestenosis differences.Results: in the randomly selected827cases, there were129cases of coronary stent restenosis, the restenosis rate of the coronary stent was15.60%. Analysis showed that restenosis groups in gender, age, smoking,hypertension, diabetes, hypertriglyceridemia, hypercholesterolemia, highLDL-C, clinical diagnosis, emergency PCI, intraluminal thrombus,bifurcation lesions, adverse events, and so the differences were notstatistically significant (p>0.05). There were1247stents in the treatmentof coronary artery disease,226of them had restenosis, and the restenosisrate was18.12%after stenting.. Restenosis group compared with norestenosis group, restenosis group stent diameter, stent length, stentnumber (p<0.05). There was no significant difference between the twogroups in the lesion site, blood vessel, Yu Kuozhang (pre dilated number,pre dilated pressure) and after expansion (the number of expansion afterexpansion, and after expansion pressure).. Will high cholesterol, clinicaldiagnosis, emergency PCI, bifurcation lesions, adverse events, predilation, stent diameter, stent length, severity and stent number logisticstepwise regression analysis. Among them, the diameter of the stent, stentlength, number of stents for in stent restenosis independent risk factors (P<0.05).51cases of restenosis in patients with gender, age, hypertension,diabetes, hyperlipidemia hyperlipidemia, smoking and the lesion sitedifferences had no statistical significance (P>0.05), stent implantationrestenosis patients were lower than that of the single balloon dilatation,the difference is statistically significant (P <0.05).Conclusion: stent restenosis is related to stent diameter, stent length, and number of stents.. The risk factors of stent length, the number ofstents were restenosis in the stent. The protective factors of the largerstent diameter are the stent restenosis. The effect of different treatmentstrategies on the prognosis of stent restenosis was superior to that ofballoon dilatation after stent implantation.
Keywords/Search Tags:Coronary heart disease, stent restenosis, risk factors, treatmentstrategy
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