Tang Yi Ping Recipe To Change The Intervention Study Of Impaired Glucose Regulation And The Effects On Rat Glucagon

Objective: to observe the different square to change the sugar in patients withImpaired glucose regulation (IGR) and curative effect of interference from the rats and itsmechanism is discussed in this paper.Methods: a double-blind comparison,23cases of treatment group on the basis offoundation treatment to different sugar square (traditional Chinese medicine (TCM) by1:5volume than soaked in water for30min,40min decoction, twice decoction, leachingsolution about300m1twice, one time in the early to middle temperature, a dose).Control group22cases, on the basis of the same basic treatment with metforminhydrochloride enteric-coated metformin hydrochloride250mg each time, three times a day,oral. Both groups to40days for a period of treatment, observation2course of treatment.All cases before and after treatment to observe the fasting glucose, fasting insulin, andcalculate the HOMA-IR values, glycosylated hemoglobin, OGTT test, determination of30min, insulin, blood sugar2h blood glucose, insulin, blood lipid (TG, TC), urine routine,liver and kidney function, electrocardiogram inspection, symptoms and signs. All caseswere made after2courses of curative effect evaluation.Results: the treatment group after the intervention, fasting glucose, fasting insulin,HOMA-IR values, glycosylated hemoglobin,30min, insulin, blood sugar2h bloodglucose, insulin, blood lipid (TG, TC), symptoms and signs changes obviously improvedthan before, such as compared with the control group with significant difference. Found noadverse reactions during the test.Conclusion: different sugar square joint interventions in patients with IGR curativeeffect is distinct, the glucose, lipid, improve insulin resistance, can significantly improveclinical symptoms in patients with IGR; Better reverse IGR and delay the development intothe process of DM, IGR and drug safety, and proves the feasibility and effectiveness of the treatment based on syndrome differentiation of traditional Chinese medicine, the correctuse of traditional Chinese medicine dialectical treatment to improve the glycometabolismhas the very broad prospects.