Clinical Observation Of Diarrhea Type Irritable Bowel Syndrome Of Liver Stagnation And Spleen Deficiency Syndrome

Object: The clinical study and observation of self-made prescription intestinal Decoction in the treatment of diarrhea type irritable bowel syndrome with 60 clinical efficacy and safety,and from two aspects of theory and clinical research systematically explore Shugan Jianpi method in treating diarrhea type irritable bowel syndrome mechanism.Methods: Select 60 patients met the inclusion criteria were randomly divided into treatment group and control group,each of 30 Cases.In the treatment group and the decoction of the decoction,one day and one dose,two times in the morning and evening.The control group and Trimebutine Maleate Capsules oral,1 tablets 1 times,3 times / day.Two groups were eight weeks of continuous medication for a course of treatment.After 8 weeks,the two groups were compared before and after treatment of TCM symptoms,IBS-SSS scale score,before and after the IBS-QOL scale integration,and after the PRO scale integral comparison.The patients were followed up for 8 weeks after the end of treatment,and the recurrence of the patients were observed.Results: 1.Comprehensive efficacy: treatment group were cured in 6 cases,8 cases were markedly effective in 12 cases,4 cases,the total efficiency of 86.7%;control group cured in 2 cases,8 cases were markedly effective in 8 cases,12 cases,the total efficiency 60%.Treatment group,the total effective rate higher.2.Experimental group before and after treatment IBS-SSS scale score,there was a significant difference(P<0.01);the control group before and after treatment of IBS-SSS scale score compared with a significant difference(P<0.05);after treatment in the control group and the test group IBS-SSS scale score comparison,there was a significant difference(P<0.01).3.No pre-treatment,the TCM symptom score significantly different(P>0.05),comparable;treatment group before and after treatment each TCM symptom scores were significantly improved(P<0.05),compared with the control group in addition to abdominal pain before there varying degrees of improvement in symptoms compared with the rest of the front,no significant improvement(P>0.05).4.Before treatment groups TCM symptom total score was no significant difference(P>0.05),comparable in the total score before and after treatment group differences(P<0.05),comparable,indicating that the two groups are valid,the two groups after treatment total score was significant difference(P<0.05),comparable,the treatment group in relieving symptoms of TCM effective than the control group.5.Before treatment showed no significant difference(P>0.05)between the two groups IBS-QOL 8 dimensions integration group,the groups were comparable.In the control group only health concerns,integration before and after family ties two dimensional treatment differences,the remaining dimensions no significant difference between the treatment group only in family relationships,heterosexual concept before and after treatment points no significant difference(P>0.05),the rest showed a significant difference(P<0.05).6 Before treatment groups PRO scale dimensions 6.points showed no significant differences,suggesting that the scale of the two groups were comparable at baseline,after treatment,the two groups of six dimensions Scale scores were lower,but the treatment group in the system state,reflux,bowel,indigestion 4 dimensions scores than the control group showed a significant difference(P<0.05),the treatment group in the system state,reflux,bowel,indigestion four areas has been greater improvement.7.Recurrence rate: followed up for 2 months in the process,the treatment group,the recurrence rate was 11.5%,the recurrence rate was 44.4% in the control group,suggesting that security intestine soup treatment of diarrhea-predominant irritable bowel syndrome can reduce the recurrence rate,good long-term efficacy,application and worth further push.Conclusion:Compared with the control group,the treatment group can significantly improve the IBS-SSS scale integration,improve the symptoms of TCM,IBS-QOL scale integration,PRO scale integration.In summary,an Chang Decoction "in the treatment of diarrhea type irritable bowel syndrome clinical comprehensive therapeutic effect is better than that of trimebutine trimebutine maleate capsules,and long-term curative effect good,can reduce the recurrence rate,improve the patient’s quality of life,worthy of further application and popularization.