Research And Animal Esperimental Study Of A Modified Bone Marrow Puncture Infusion Needle

Along with social development, the number of vehicles increasing quickly in ourcountry. More and more patients due to car accident in city.Due to the constriction of firstaid，intravenous access could not timely be established in pre-hospital or emergencyroom, drugs could not be input to rescue patients.A lot of patients lose valuable time tobe saved.Intraosseous access has been used for more than90years since twentiethCentury twenty’s when it was first introduced. Intraosseous access may be used as asecond choice in emergent situations in which intravenous access is not attained. Severalforeign intraosseous device has been invented and widely used by clinicians, butthere is no domestic products. When compared the advantages and disadvantages ofthese device, we redesigned the intraosseous equipment and test its practicability inanimals.Part oneIntroduction of modified self-designed intraosseous needle insertion device andpatent applicationOBJIECTIVE: modify an introssous needle and apply for state new type practicalapplication patentMETHODS: Design and improvement of an introsseous equipment by comparingadvantages and disadvantages of the existing introsseous devices.RESULTS: We have successfully redesigned an introssous device and obtained astate new type practical application patent.Part twoBACKGROUND AND OBJIECTIVE: To evaluate the resuscitation effect ofhemorrhagic shock in dogs via a modified intraosseous needle insertion device.METHODS AND RESULTS: Twelve healthy male Beagle dogs weighed8-11kgwere randomized into two groups (6in each group): hemorrhagic shock group as controlgroup and resuscitation modified intraosseous needle group as experimental group. Thefemoral artery was cannulated to monitor arterial pressure as well as for control thebleeding. Sodium Chloride Solution were infused Intraosseously through distal femur cavity in the Experimental group, while dogs in the control group were treated withouttransfusion. Changes of mean arterial pressure (MAP),heart rate(HR), hemoglobinConcentration (Hb) and hematocrit (Hct) were monitored peri-resuscitation.During hemorrhagic shock stage, MAP, HR, Hb and Hct were decreasedsignificantly, while no significant difference was found between groups (P>0.05). Duringresuscitation phase,30min,60min,90min postshock, MAP in experiment groupsignificantly decreased at each time point as compared with that in control group(P<0.05),while HR, Hb, HcT in experiment group were significantly higher than that incontrol group (P<0.05). Methylene blue solution were infused through the intraosseousneedle infusion, no fluid extravasation occured.CONCLUSION: The modified self-designed intraosseous needle insertion devicewas effictive in hemorrhagic shock in dogs. Part threereviewBACKGROUND: Introduction of history and development of intraosseous(IO)technology.OBJECTIVE: Article describes the current widely used IO devices, puncture sites,indication，complications, contraindications and comparion of use of different devices,the use of IO in current in world.DISCUSSION： the prehospital use of IO technology has become the maindirection of current research in world.CONCLUSION：Pre-hospital care and military health organizations should bestrengthened to learning IO，using IO widely as possible in the country.