Five Constant/Trace Elements Analysis In The Blood Of Children With Diarrhea

ObjectiveBy detecting the contents of five common and trace elements (iron, zinc, copper, magnesium, calcium) in healthy children and ones with diarrhea, the relationship between diarrhea and five blood elements in children was explored in patients with diarrhea and healthy subjects and the correlation between children with diarrhea and healthy ones in different age was also investigated. The results could provide reliable evidence for the role of common and trace elements in the occurrence and development of diarrhea and revealed that the situation of elements should be considered in the treatment of diarrhea.MethodsA retrospective analysis includes63cases of diarrhea children from Liaocheng People’s Hospital and200cases of healthy children from Child Health Care Department. The five elements (Fe, Zn, Cu, Ca, Mg) in the blood of the subjects were determined by five-channel atomic absorption spectrometer (BH-5100, produced in Beijing Bohui Innovation Technology Co. Ltd). The data were analyzed by SPSS16.0software, and measurement data used t-test and count data used χ2test,Result1. Through the detection of Cu, Zn, Ca, Mg and Fe levels in diarrhea and normal control groups and the analysis by statistic software SPSS17.0it was found that the Ca and Mg levels of diarrhea group were significantly higher than normal control group (P<0.01). Fe and Cu in diarrhea group were slightly higher and Zn was slightly lower than those in normal control group but without statistic significance (P>0.05).2. The results between male and female in diarrhea group or in normal control group showeds no significant difference (P>0.05). However, when compared to healthy subjects Ca and Mg were significantly higher in male of diarrhea group than those of normal control group (P<0.01), while Cu and Zn were slightly lower and Fe was slightly higher in male of diarrhea group than that of normal control group (P>0.05). Mg and Fe were significantly higher in female of diarrhea group than that of normal control group (P<0.01), while Ca and Cu were higher and Zn was lower in female of diarrhea group than those of normal control group (P>0.05).3. The significant results differences between diarrhea group and normal control group of different age have not been found (P>0.05). And in diarrhea group age might imposes little influence on the levels of the five elements (P>0.05).Conclusion:In diarrhea of children, the blood Ca, Mg and Fe increased significantly, in male patient Ca and Mg increased while in female patient Mg and Fe increased. On the other hand, Cu and Zn showed no significant difference between patients and normal subjects. Detecting the blood levels of Ca, Mg and Fe could be important to diagnose and treatment of diarrhea children.