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Analysis Of The Reliability Of The Application Of Trinal Room Ultra-high Field Intraoperative Magnetic Resonance Imagingsuite With A Movable Magnet For Glioma

Posted on:2016-10-28Degree:MasterType:Thesis
Country:ChinaCandidate:H B LiuFull Text:PDF
GTID:2284330467997313Subject:Surgery
Abstract/Summary:PDF Full Text Request
Objective:By comparing tumor resection rate of tumor patients adoptedintraoperative MRI assisted resection and patients with normal performerexperience removal, and postoperative neurologic deficits andpostoperative infection of both, to analyze the operative reliability ofmoving magnet high field strength of intraoperative magnetic resonancein glioma operation.Method:Select all30patients received glioma operation adopt iMRI in ourdepartment as experimental group, and randomly select30cases receivedexperience resection operation during this period as control group. Tumorresection rate of two groups are calculated respectively [(preoperativetumor volume-postoperative residual tumor volume)/preoperativetumor volume]. Arrange follow-up visits on patients of two groups andseek case history to obtain whether the postoperative patients with orwithout neural function defect and change, refer to scale scoring of "National Institute of Health Neural Function Defect Scale”; make statistics of two groups of postoperative patients with intracranialinfection, respectively. To evaluate the effects of iMRI on resection rateof gliomas, the value of iMRI for important nerve and blood vesselprotection by comparing the three data from the experimental group andcontrol group, and whether iMRI would increase the risk of infectionduring operation as well, so as to analyze the reliability of intraoperativemagnetic resonance applied to glioma.Results:The comparison of tumor resection rate of two groups: averageresection: experimental group (98.1%)> control group (94.2%). Totalremoval rate of tumor: experimental group (66.7%)> control group(50%); subtotal tumor resection rate of patients with tumor subtotalremoval operation: experimental group (94.3%)> control group(88.%);the variation analysis of tumor resection rate of both groups hasstatistical significance(p=0.037<0.05).Comparison of neural functionscore: conduct postoperative neural function rating on patients from bothgroups according to NIHSS, the average score of experimental group (0.7)<of the control group (1.4);10cases appeared function defect withdifferent degree in experimental group (10/30), while14cases appearedfunction defect with different degree in control group (14/30). The data oftwo groups has no statistical significant due to the lower quantities ofsamples and smaller differences of the data (p=0.178>0.05), but it is shown that the application of iMRI can obviously reduce the damage toneural function. Infection in postoperative patients comparison: thepostoperative infection rate of patients received iMRI in glioma operationis same with the postoperative infection rate of patients received generalglioma operation,that is6.7%(2/30).there is no difference between thetwo goups.Conclusion:Intraoperative MRI applied in surgical treatment of glioma, which canobviously increase the tumor resection rate, whilst has certainsignificance for neural function protection, and basically the risk ofinfection of which won’t be increased in glioma operation. iMRI appliedto the glioma operation has certain reliability.
Keywords/Search Tags:Intraoperative MRI, Glioma, Resection rate, Neural function, infection
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