| ObjectiveAs obesity becomes increasingly serious health problems, determinations of the content of fat and fat tissue, and their distributions are becoming research hotpots. Muscle is closely related to substance and energy metabolisms in the body. Metabolic syndrome is a common metabolic disease associated with obesity, the high prevalence of which makes it a serious public health problem in China. The community people in Hangzhou were adopted as the research objects. Plasma phospholipid fatty acid, fat distribution, and clinical indicators reltated with metabolic syndrome in the body were measured from the perspective of dietary nutrition. Fatty acid and fat distribution related indicators, as well as relevant clinical indexes were analyzed to study the relationships between the body composition of fatty acid as well as fat distribution with metabolic syndrome.Materials and Methods108research subjects were recruited from communities in Hangzhou during the period of2008-2013. The social demographic data were collected by using questionnaires. Measurements of physical data (height, weight and waist circumference and other indicators), Magnetic Resonance Imaging(MRI), blood biochemical indicators, and plasma phospholipid fatty acids were carried out. Correlation analysis, multiple linear regression analysis, and dichotomies Logistic regression were used as the methods to study the relevances between plasma phospholipid fatty acid and body composition as well as metabolic syndrome, respectively.Results102research subjects are included in this study. The average age of the objects was52.10±12.55, in which male was51.17±13.75and female was53.23±10.96. No statistical difference was found between two age groups. The total VAT, IMAT and Muscle, abdominal VAT, IMAT, and Muscle, waist circumference, systolic pressure, diastolic pressure, fasting glucose and cholesterol in male are significantly higher than those in female, while the total SAT and abdominal SAT in male are remarkably lower than that in female. No obvious differences of age and BMI between male and female are observed. Significant differences in the indicators such as fat distribution between male and female exist. Male and female have significant differences in waist circumference, systolic pressure, diastolic pressure, and fasting glucose, while no obvious differences in triglyceride, HDL, and incidence rate of metabolic syndrome. The relative concentrations of plasma fatty acids C17:0and C20:2in male are significantly lower than those in female, while the relative concentrations of C18:3(RLA), C20:3n3, C20:4(AA), and C22:4are in the reverse. No statistical difference is found between other types of fatty acids in male and female. The results of regression analysis show that C14:0is positively related to total IMAT, and C17:0is negatively related to total VAT and total IMAT in male group. No relevance is found between fatty acid and IMAT in female group. In male group, C16:0, C18:0, and SFA are positively related to muscle, while no relevance in female group. C12:0, C20:0and C22:6(DHA) is negatively related to metabolic syndrome. No significant association are found between n-6fatty acids and metabolic syndrome.Conclusion1. Total VAT, IMAT, and Muscle, abdominal VAT, IMAT, and Muscle in male are higher than those in female, while total SAT and abdominal SAT are in the reverse.2. In male group, higher content of C14:0indicates more total IMAT, while higher content of C17.0indicates less total VAT and total IMAT. In female group, no relevance is found between fatty acid and IMAT.3. In male group, higher contents of C16:0, C18:0, and SFA indicate more muscle content, which means intake of saturated fatty acid can prevent sarcopenia. In female group, no relevance between fatty acid and muscle is found.4. The use of C12:0, C20:0, C22:6(DHA) could potentially benefit MS by reducing risk factors. No significant association are found between n-6fatty acids and metabolic syndrome. |
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