Effect Of Different Strengthening Nutrition Strategies On Growth Development Of Premature Infants After Discharge

Objective:To compare the difference of the growth index, body fat content and skinfold thickness, biochemical assessments and serum Insulin-like Growth Factor 1 (IGF-1) of preterm infants under the different strengthening nutrition design.Method:75 preterm infants admitted to the NICU of First Affiliated Hospital of Kunming Medical University from November 2013 to August 2014 were collected and reviewed. Took the unified early nutrition support on the low birth weight infants until their vital signs were stable enough for discharge. Then the preterm infants were randomly divided into 2 groups. According to the different group, they were accepted different enrich nutrition design (group A were enriched nutrition until they reached 40 weeks corrected age, while group B were enriched until their weight index reached the 25th percentile on growth charts with corrected age), and were switched to half enriched nutrition after that. The two group were evaluated and compared when they reached 40 weeks,1 month,2 month,4 month,6 month,8 month in corrected age with growth index, body fat content and skinfold thickness, biochemical assessments and serum Insulin-like Growth Factor 1 (IGF-1).Results:No significant differences were observed between enriched nutrition to reach 40 weeks corrected age and enriched nutrition to weight index reach the 25th percentile on growth charts with corrected age in terms of growth, nutritional status, body fat content and skinfold thickness, Insulin-like Growth Fact 1(P>0.05).The growth index (weight, height, head circumference) of group A had a faster catch-up growth until 3-4 months corrected age and the body fat content variance was significant at 6 month corrected age, while group B had a slower catch-up growth before 3-4 months corrected age and the body fat content was very concentrated at 6 month corrected age. But that differences were not significant by 8 month corrected age.Conclusion:No significant differences were observed between the two strengthening nutrition designs. The condition of preterm infants are vary, so the design of feeding methods should depends on individuals, by this way can try to optimize their catch-up growth.