Studies On The Preparation Process And Quality Standard Of Liangxue Huoxue Soft Capsules

Objective : for dosage form reform of Liangxue Huoxue Decoction, the establishment of extracting molding process stable and perfect quality control system, the modernization of traditional Chinese medicine preparation for Liangxue Huoxue soft capsules to get safe, efficient, stable, controllable, high technology content.Methods : this subject is studied through orthogonal experimental design on the extraction of medicinal materials of cooling blood and activating blood circulation in soft capsule. Selection of high bioavailability, good sealing performance, accurate dosage soft capsule as a drug dosage form, and through the key parameters on the content of compound prescription preparation process, capsule shell were optimized by single factor experiment design; Using the method of TLC to control drug and control products for the control of the main medicinal products were studied in the qualitative identification HPLC was used to determine the content of Rutin in which the main effective components;Preliminary study on the stability of preparation experiment.Results : to determine the technology of extraction and refinement of various ingredients in the preparation of party, forming process, the method of content determination of formulated the qualitative identification method of various ingredients in the party and main effective component, and the preparation was studied preliminary stability.Conclusion : Cooling blood soft capsule prescription is reasonable, scientific andadvanced extraction preparation process, quality standard strictly controlled, efficacy sure,high technology content, accord with the request of the modernization of Chinese medicine,and has a broad market prospect.