Clinical Study Of Tang Shen Sheng Qing Jiang Zhuo Granules Impact On CysC And UMA In Diabetic Nephropathy Proteinuria Period

Observation Tang Shen Sheng Qing Giang Zhuo granules on diabeticne phropathy proteinuri Cys Cand U-MA the influence of validation Tang Shen Sheng Qing Jiang Zhuo granules the clinical curative effect of treatment of diabetic nephropathy proteinuria period, exploring stage diabetic nephropathy proteinuria of traditional Chinese medicine treatment of the optimal combination of the formulas.Methods 60 patients with diabetic nephropathy will conform to the requirements of the selected cases according to the doctor order randomly assigned into the treatment group and control group, treatment group 30 cases and control group 30 cases. Treatment group given Tang Shen Sheng Qing Jiang Zhuo granules + base treatment, control group given basic treatment. All patients were given the diabetes health education doing proper sports strict diet, ensure proper calorie intake daily protein intake in 0.8g/kg,maintain positive nitrogen balance. 2 months observation records in the two groups before and after treatment of Cys C, U-MA 24 hour urine protein quantity and Scr(serum creatinine) numerical symptoms before and after treatment, fill in the clinical observation table. The data for statistical processing.Results(1) the two groups before treatment Cys C U-MA 24 hour urine protein quantity Scr is no statistical difference show two groups of comparable; Two groups before and after treatment treatment significantly lower Cys C U-MA 24 hour urine protein quantity Scr statistics to compare two groups before and after treatment treatment Cys C U-MA 24 hour urine protein quantity Scr has significant difference that two groups of treatment are effective; Comparing the two groups after treatment of Cys C,U-MA,24 hour urine protein quantity Scr has significant difference,suggests that the treatment group curative effect is better than the control group.(2) Tang Shen Sheng Qing Jiang Zhuo granules cooperate with western medicine treatment group 22 cases were markedly effective effective 7 cases 1 had no effectthe total effective rate 96.7% the western medicine control group 15 cases were markedly effective 6 cases effective 9 no effect the total effective rate was 83.35%;Compared two groups have significant difference(P < 0.05). TCM symptoms total integral comparison the two groups after treatment of traditional Chinese medicine symptom integral were significantly reduced in the same group there was a significant difference compared with before treatment after treatment. TCM symptom score between the two groups after treatment compared with significant difference(P< 0.05) the treatment group is superior to western medicine control group.Conclusion Clinical studies have shown that Tang Shen Sheng Qing Jiang Zhuo granules treatment of diabetic nephropathy qi and Yin deficiency turbidity toxin holds the curative effect is distinct can significantly improve patients’ Cys C U-MA 24 hour urine protein quantity and S-cr laboratory indexes such as clinical symptoms improved significantly stage diabetic nephropathy proteinuria have obvious advantages than the control group is a kind of agent for treatment of diabetic nephropathy better combination can be widely used in clinical.