| Objective: To observe the kidney Tim refined Kun Ann decoction of kidney research perimenopause affect the clinical efficacy and lipid metabolism in patients(peripheral menopause syndrome PMS) Syndrome,, providing clinical evidence for chinese medicine treatment of perimenopausal syndrome, clinical the work.Methods: Follow the method itself controlled clinical study, included 30 cases of patients with kidney PMS, giving YSTJR Kun security decoction, 2 times a day, each 1 bag(200ml), a course of 3 months. TCM clinical syndrome observed in patients before and after treatment of climate change(using kidney perimenopausal syndrome symptoms grading quantitative criteria, see Appendix 2), improvement of clinical symptoms(using domestic modified Kupperman scale score, see Appendix 2), hormone(FSH, LH, E2) and plasma lipid(TC, TG, HDL, LDL) levels, waist-hip ratio(WHR) level.Results:(1) patients after treatment symptom score, Kupperman score decreased significantly than before, P <0.01, the difference was statistically significant; serum FSH levels and LH levels(2)patients decreased significantly after treatment than before, P <0.05, the difference was statistics significance; E2 levels have shown a rising trend, but compared with before treatment, P> 0.05, the difference was not statistically significant.(3)patients after treatment TG, LDL, TC levels than before the decline, HDL levels were significantly increased compared with the previous, P <0.05, the difference was statistically significant.(4)patients after treatment WHR level decreased than before,P <0.01, the difference was statistically significant.Conclusions:(1) Kun An kidney decoction can significantly improve the clinical symptoms of perimenopausal syndrome.(2) Kun An decoction can regulate kidney perimenopausal syndrome with serum hormone levels.(3)Kun An decoction can improve kidney perimenopausal lipid metabolism of patients with the syndrome.(4) Kun An decoction can reduce kidney perimenopausal syndrome waist-hip ratio levels. |