| Objective: To study the therapeutical effect of the decoction of Yi-shen-tiao-geng on peripheral menopause syndrome(PMS), and to explore its action mechanism. Methods: We selected 60 patients with PMS, observe the clinical symptoms' improvement after treatment and detect the concentration of E2,FSH,LH,β-EP,PTH,CT,IL-2 in the blood. Results:The clinical symptoms are significantly improved and the clinical total efficiency is 98.33%.The improvement of Kupperman scores is very significant (P<0.01). After treatment, the concentration of FSH, LH in the blood is lowered, while the concentration of E2 in the blood is raised (P<0.05). The concentration ofβ-EP,CT,IL-2 is significantly evaluated after treatment,while the PTH are remarkably reduced(P<0.05). Conclusions: Yi-shen-tiao-geng on peri-menopausal period of liver syndrome has good therapeutic effect, Can effectively relieve sometimes hot flashes sweated, sometimes chills, waist knees ache, insomnia and have many dreams wai menopausal symptoms, its role is to correct the disorder from the whole of the endocrine and autonomic disorders to improve the imbalance of bone metabolism, is a comprehensive treatment of menopause certificate valid prescriptions. |
