Cohort Study Endpoint Hospital Of 313 Cases During The Follow-up Of Patients With Coronary Heart Arrhythmia Condition

OBJECTIVESThe hospital of traditional Chinese Medicine of coronary heart arrhythmia endpoints survey follow-up of patients discharged during the occurrence, correlation analysis, to provide medical treatment of coronary heart arrhythmia evidence based medicine medical treatment and the end of the event happening.METHEDSApply a cohort study design.Production of "Chinese Medicine Hospital cohort study of patients with coronary heart arrhythmia questionnaire." Through the hospital medical record information management system, select the Affiliated Hospital of Shandong University of Traditional Chinese January 1, 2008 to December 31, 2013 hospitalized patients admitted to coronary heart arrhythmia, conduct medical record investigation. Telephone follow-up, combined with outpatient follow-up, Follow-up of patients after discharge 3 months, 6 months, 1 year, 2 years,recording oral medicine, decoction application and endpoint events occurred after the patient was discharged, the filled questionnaire follow-up section.Epidata software selection, Chinese Medicine Hospital established coronary heart arrhythmia cohort study followed up information databases, data entry, and export data to Excel table. Occurrence statistics exposure group(≥28 days by application of traditional Chinese medicine) the end of the event, the application of multivariate logistic regression analysis, correlation between medical treatment and the end of the event.RESULTS1.Follow-up Survey of 386 cases of hospitalized patients with coronary heart arrhythmia, complete follow-up of 313 cases, 18.91 percent dropout rate. The average follow-up time(14.86 ± 10.64) months, the longest 66 months, a minimum of 10 days. The average age of the patients(62.35 ± 8.65) years old, male 140 cases(44.73%).2. Chinese medicine treatment exposure group(use of oral medicine and traditional Chinese medicine decoction ≥28 days) 194 cases, accounting for 61.98%, which is greater than or equal to 6 months in 82 cases, accounting for 26.20%. Decoction of oral medicine and important to Shensongyangxin capsule and Shengmaisan, accounting for 35.29% and 33.93% respectively.3. endpoint events were happening endpoint of cardiovascular readmissions 123(39.30%) patients with acute heart failure, 36(11.50%) patients, stroke 31(9.90%) patients, all-cause mortality 16(5.11%) cases myocardial infarction, 13(4.15%) cases and so on.Coronary heart arrhythmia primary endpoint follow-up medical treatment evaluations including all-cause mortality, sudden death, cardiac arrhythmias, secondary endpoints include cardiovascular readmissions, acute heart failure, stroke, myocardial infarction.4.logistic regression show application of Chinese medicine to reduce cardiovascular readmission(OR = 0.731), and the risk of stroke(OR = 0.544) in. Tips sufficient strength in Chinese medicine treatment can reduce cardiovascular readmissions, stroke event rate. In addition, people with high blood pressure can increase mortality(OR = 8.537); patients with diabetes can increase the risk of myocardial infarction(OR = 3.021).CONCLUSIONSCoronary heart arrhythmia patient was discharged after the end of the main event for all-cause mortality, acute heart failure, myocardial infarction, cardiovascular readmissions, stroke, etc; cardiovascular readmission application of Chinese medicine treatment can reduce the follow-up period, the occurrence of stroke events.