Distribution Characteristics And Correlation Analysis Of 200 Cases Of MA Patients With The Lack Of Folic Acid And VitB₁2

Objective: Retrospective analysis of the common index of clinical detection and the lack of folicacid/Vit B12 with the MA patients in our hospital in December 2005-December 2013, to have a further understand the characteristics of the disease. Methods: 1. Confirming the time range, included in the standard and exclusion criteria for the cases. 2. According to the medical record management system by computer and medical record room to collect the related cases which are fixed into standard. 3. According to the basic information of cases, record the information data which we need. 4. According to the data statistical analysis, draw the conclusion. Results: 1. To the statistical analysis, there are differences with gender composition in different age groups, and there is no difference between different genders as a whole. 2. With the pathogenic factors, chronic gastritis and improper diet are in a total of 159 cases, about 79.5%, accounted for the vast majority of patients. 3. In 200 patients with MA, mixed anemia, a total of 12 cases, about 6% of the all. 4. In the patients of MA, the patients with moderate anemia and severe anemia are in total of 176 cases, about 88%. With the results of determining the folic acid and vitamin B12, at least one of them is deficiency in a total of 168 cases, about 84%, including the lack of folic acid 34 cases, about 17% and the lack of vitamin B12 107 cases, about 53.5%. According to the statistical analysis, different degrees of the lack of folic acid and vitamin B12 have no different influence on the degree of anemia. 5. In this 200 cases, there are only 2 cases with red blood cells, white blood cells and platelets are all normal, but the Hb of these 2 cases is lower than the normal. The abnormal of red blood cells is the most common, and their content is reduced, a total of 194 cases, about 97%. According to the statistical analysis, the lack of folic acid and vitamin B12 has different influence on red blood cells, white blood cells and platelets. 6. The assay of direct bilirubin and indirect bilirubin in the peripheral blood, there are 144 cases with that at least one of them is abnormal, a total of 72%. 7. In 167 patients with MA, there are 122 cases with CA15-3 positive, about 73.1%. According to the statistical analysis, ①folic acid and CA15-3are related, the less chance of the folic acid is lack, the greater chance of CA15-3 is positive; ②Vitamin B12 and CA15-3 are related, the more chance of the vitamin B12 is deficiency, the greater chance of CA15-3 is positive. Conclusion: 1. The majority of 200 MA patients who were in hospital have the deficiency of vitamin B12. Different degrees of the lack of folic acid and vitamin B12 have no different influence on the degree of anemia. 2. With the MA patients, the lack of folic acid and vitamin B12 has influence on red blood cells, white blood cells and platelets. And they have the biggest impact on red blood cells. The MA patients are most of moderate anemia and severe anemia. 3. CA15-3 with folic acid and Vitamin B12 are all related.