| Objective:To evaluate the nutritional status of children with cancer at dignosis and after 2 months of treatment, providing evidence for Nutritional intervention.Methods:36 paediatric patients with solid malignancies and 36 sex, agematched non-cancer patients who visited the First Hospital of Jilin Uniwersity from August 2014 to December 2016 were enrolled into this clinical trail.Clinical data included the patiens’ and the controls’ anthropometric indexes involving height,weight and biochemical criterins involving prealbumin,retinol conjugated protein,creatinine and trigelyceride. For comparison of anthropometric status and biochemical criterins between cancer patients and their matched controls, cancer patients at dignosis and 2 months after diagnosis. An unpaired t-test was used for analysis of normally distributed variables to evaluate the nutritional status of cancer patients at dignosis and during treatment.Relsults:1. The morbidity of malnutrition at dignosis is 5.5%,and rise to 11.1%after 2 months of treatment.2. The patiens’ height,weight and BMI are all under the controls’, but the differences were not significant.3. The cancer group tended to have higher retinol conjugated protein,creatinine than did the control group,but of which only the retinol conjugated protein was significant(P<0.05).4. The BMI and weight Z scores of cancer group decreased after 2months of treatment,the difference was significant(p<0.05).5. The prealbumin and retinol conjugated protein increased after 2months of treatment,the difference in retinol conjugated protein was significant( p<0.05),the creatinine decreased, but the difference was not significant.The trigelyceride increased,and the difference was statistically significant(P<0.05).Conclusion:1. Children with cancer have equal height, weight, and BMI with their peers.2.Chemotherapy can result in malnutrition, change the body composition and make the fat mass increase.3.Nutritional intervention is suggested for children undergoing treatment of Cancer. |
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