Eosinophilic Chronic Rhinosinusitis With Nasal Polyp In The North East Part Of China

INTRODUCTION AND OBJECTIVES:Chronic rhinosinusitis(CRS), an Inflammatory disease of paranasal sinuses and nasal passages persisting more than 3 months is now one of the most common Ent diseases in china with an overall prevalence of 8% in the general population. CRS is currently classified into CRSw NP(with nasal polyp) and CRSs NP(without nasal polyp). The majority of the CRSw NP cases have a strong tendency to reoccur after the surgery and show eosinophilic-dominant inflammation, so based on the presence of tissue eosinophlic infiltration or not, The CRS is further divided into eosinophilic CRS and non-eosinophilic CRS. ECRS commonly demonstrates more severe symptoms, polyp diseases with a higher incidence of bilateral polyps and sinonasal diseases on computed tomography, and the increase in the blood eosinophils. The differentiation of the specific subtypes and clinical features of CRS will be important for developing better treatments methods and might infact improve the treatment outcomes for individual phenotypes of CRS.METHODS:In the research, we have collected CTscans, Blood samples and there pathological tissue sample reports and nasal smear cytology for past 3 years(i.e 2013-2015). A total of 113 patient’s reports were studied and compared(i.e 69 males and 44 women) belonging to CRS, NP and others related to CRS where also taken in the consideration. In the CTscans, we used lund-mackey points system as a criterion standard for symptomatic assessment of the CRS for a diagnostic accuracy RESULTS:The ECRS is the clearly differentiated with the non-ECRS, by looking at the nasal smear cytology examination report,the CT scans also show the ethmoidal sinus shows more Opacification for ECRS and for non-ECRS(NCRS) its maxillary sinus which doesn’t show any change. CONCLUSION:Chronic rhinosinusitis is still a very important subject to be researched more about, as we know it is divided into two types ECRS and NECRS with or without nasal polyps(mostly associated with the nasal polyps) these ECRS and NECRS have different clinical diagnosis and treatment. Even though there is no universally accepted Diagnostic criteria for ECRS and also the pathological factors of ECRS are still to be understood well so that there will be a better way for treatment for the CRS on whole...