Study On The Correlation Between BODE Index And The Severity Of Chronic Obstructive Pulmonary Disease

Objective: To explore the BODE index and chronic obstructive pulmonary disease（COPD） patients with onset age, length of hospital stay, within 1 year after discharge acute exacerbation, hospitalization, C-reactive protein（CRP） and arterial oxygen partial pressure, partial pressure of carbon dioxide in the correlation. To analyze the correlation between the BODE index and the severity of COPD, and to provide a new way of thinking for clinicians to evaluate the severity of COPD.Methods: From January 2014 to January 2015, 189 COPD patients hospitalized in the respiratory department of internal medicine, First Hospital of Jilin University Bethune cases, the average age（64+11） years old, of which 92 cases were male, 97 female Diagnostic criteria with 2015 chronic obstructive pulmonary disease Global Initiative for the guideline of prevention and treatment; collecting general information of patients and BODE index 4 indexes, through access to medical records of patients registered sex, age, residence, smoking history, hospitalization days, year of onset and other. < estimated 80% were calculated and the BODE index score: bode grade I（0-2）; level II（3-4 points）; grade III（5-6）; IV（7-10） according to the BODE index values into the group of 189 cases of patients were randomly divided into four groups: group A: 0; group B: 3-4; group C: 5-6 minutes; group D: 7-10. According to FEV1% predicted values were randomly divided into 3 groups: I group(50% less than or equal to FEV1< value II Group（30% is less than or equal to% FEV1 < 50% predicted value）; group III（FEV1% 30% of predicted value）. Record the patient’s age, the length of hospitalization, arterial oxygen partial pressure, carbon dioxide partial pressure, serum C reactive protein level, after 1 years of follow-up, the number of acute exacerbation and hospitalization. Compare the differences between the groups.Result:（1） BODE index group, each group of PO₂, PCO₂, CRP, length of stay, duration of disease, the number of acute exacerbation, length of stay, P<0.05, the difference was statistically significant.（2） grouped in FEV1%, among the groups PO₂, p CO₂, C reactive protein（CRP）, course of disease, acute exacerbation, P<0.05, each group have statistical significance, which length of hospital stay, hospitalization times between group differences, P>0.05, the difference was not statistically significant.（3） BODE index was negatively correlated with PO₂, and CRP, the number of acute exacerbation, hospitalization times, PCO₂, length of stay, the duration of the disease were positively correlated. FEV1% and arterial oxygen partial pressure is positively correlated with CRP, PCO₂, acute exacerbation frequency, duration of negative correlation, and the length of stay, hospitalization frequency no correlation.Conclusion:（1） BODE index may be able to evaluate the severity of the disease in patients with chronic obstructive pulmonary disease.（2） BODE index may be able to predict the prognosis of patients with chronic obstructive pulmonary disease.（3） Compared with the simple application of FEVl, BODE index is a new index for a better assessment of chronic obstructive pulmonary disease severity.