Soybean Qingmai Toll-like Peripheral Side Effects Of Four And Nuclear Factor κB Signaling Pathway In Patients With Unstable Angina Receptor

Purpose:By observing Wuxi Research unstable angina (UA) clinical syndromes, Soybean Qingmai party intervention in patients with unstable angina, peripheral blood were observed and compared with pure Western standards in the treatment of unstable angina patients Soybean Qingmai party intervention Toll-like receptor 4 impact and nuclear factor-κB signaling pathway, and explore the possible mechanism of its therapeutic UA provides the theoretical basis for the preliminary Soybean Qingmai treatment of UA.Method:This topic was selected in accordance with the standard case, included 67 cases in line with 2007," unstable angina and non-ST-segment elevation myocardial infarction diagnosis and treatment guidelines " in the diagnostic criteria for patients with unstable angina, full-time practitioners accordance with the " Chinese medicine clinical research guidelines " dialectical method Noxious Heat meets stasis in patients were randomly divided into a control group and the experimental group and the control group of 32 patients in the experimental group of 35 cases. All patients were to regulate Western medicine treatment, the experimental group with Soybean Qingmai parties were the main symptoms of angina were observed efficacy of TCM syndrome before and after treatment, serum TLR-4mRNA, NF-κB inflammation levels, and blood lipid levels.Results:1.Risk stratification and TLR-4mRNA, NK-κB levels indicate different classification of angina patients with unstable angina have differences.2.0n the basis of Western UA standardized drug regimens based on the use Soybean Qingmai side can further improve clinical outcomes.3.Soybean Please vein side can inhibit the expression of TLR-4mRNA UA patients, lower serum levels of NF-κB, reduce TC, HDL levels may be elevated HDL levels, suggesting Soybean please veins party intervention in patients with UA mechanism, possibly through reduced TLR -4mRNA expression, decreased serum levels of NF-κB, regulating blood lipids, and thus inhibit the inflammatory response, stable atherosclerotic plaques.