Retrospective Study Of Postoperative Effect In OTSCC Patients

Objectives:This is a retrospective study in which the data of oral cancer patients between 2007 and 2014 in Stomatological Hospital of Shandong University were collected and sorted out. By analyzing the related factors of postoperative relapse and the survival rates of the early TSCC(tongue squamous cell carcinoma), we hope to give some suggestions in clinical treatments, prevention methods and prognosis assessments.Methods:The clinical characteristics of oral cancer patients were collected, including gender, age, tumor site, growth pattern, pathological grade, TNM stage and treatment method. The Chi-Square test was applied to estimate the correlation between the clinical characteristics and postoperative recurrence rates of early TSCC. The Kaplan-Meier analysis was applied to draw the survival curves and estimate the correlations of early TSCC survival rate in different gender, pathological grade, clinical TNM stage, treatment.Results:1. Among 193 oral cancer cases,86 cases located in tongue(44.6%),41 cases in gum (21.2%),19 cases in the palate(9.8%).18 cases in buccal(9.3%),17cases in the lip(8.8%),8 cases in parotid gland (4.2%) and 4 cases in the floor of the mouth(2.1%); male patients accounted 100 cases(51.8%), female patients 93 cases(48.2%).2. Among 77 cases of patients with early TSCC,19 cases were recurred; the recurrence rate was 24.7%. Among the factors in this study, neck dissection was seemed to closely correlate with the recurrence rate of the early TSCC patients(P=0.011). While there were no significant correlations between recurrence rate of early TSCC and gender, clinical T stage, clinical N stage, pathological grade.3. The overall survival rate in the neck dissection team was higher than in the other team(P=0.026). While there were no significant correlations between the overall survival rate of early OTSCC and gender, pathological grade, clinical T stage.Conclusions:1. The proportion of women in early TSCC patients is increased.2. We believe that the elective neck dissection is needed in the treatment of early TSCC patient. And the employment of suprascapulohyoid block resection in cNo cases can achieve the goal.