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Clinical Study On The Application Of Fast Track Surgery In Perioperative Period Of Colorectal Cancer

Posted on:2017-05-19Degree:MasterType:Thesis
Country:ChinaCandidate:L FengFull Text:PDF
GTID:2284330488986863Subject:Surgery
Abstract/Summary:PDF Full Text Request
Objective : Research on the effect of Fast track surgery in colorectal cancer surgery period, and to explore the feasibility in the colorectal cancer surgery of municipal hospital.Methods : According to the group conditions, we collected 62 routine surgery clinical data from June to December in 2015 from our hospital,depending on the treatment of perioperative, it can be divided into FTS group(n=30) and control group(n=32). FTS group patients were given perioperative regimen fast track surgery and the control group was given traditional perioperative disposal regimen. The clinical data of the two groups of patients were compared, including their age, gender, tumor location, the combined underlying diseases, TNM stage, Anesthesia ASA score, nutritional score,intraoperative conditions(blood loss, operation time), postoperative recovery( the time of exhaust, defecation and pain NRS score of 0 branch), incidence of postoperative complications(anastomotic leak, pulmonary infectioin, heart dysfunction, deep venous thrombosis, incision infection, urinary retention,urinary tract infection, postoperative ileus, abdominal distension and so on),hospital stay, hospital costs, commonly used clinical test indicators(WBC,C-reactive protein, TP, ALB) and the satisfaction of the patients in hospital.Results:1. There were no significant differences between the two groups in age, gender, TNM stage, ASA score anesthesia, nutritional score, blood lossand operative time(p>0.05), so they are comparable.2. The first exhaust time of FTS group is 63.33 ± 7.88min; the first defecation time is 84.17±8.21min; NRS pain score of 0 uses 3.82±0.66d;hospital stay is 11.63±2.16 d. The first exhaust time of the control group is97.19±11.38min; the first defecation time is 126.59±15.34min; NRS pain score of 0 uses 5.36±1.02d; hospital stay is 16.03±1.18. The time used by the FTS group is obviously shorter than control group.The differences are statistically significant(p < 0.05). The hospital costs of the two groups of patients are 2.42±0.32 ten thousand and 3.19±0.22 ten thousand; FTS group was significantly lower than the control group and the difference is statistically significant(p<0.05). Postoperative complication rate of FTS group is 13.3%(4/30), lower than the control group 28.1 %(9/32), but the difference is not statistically significant(p>0.05).After the first day of operation, the WBC of FTS group was 9.78±1.98×109/L, CPR was 41.57±17.78mg/L,while the control group was 9.78±1.98×109/L and 41.5±17.78mg/L,which is higher than FTS group. The difference is statistically significant(p > 0.05). The inflammation of FTS group is less. After the first day of operation, the TP,ALB of FTS group were 71.75±3.62 g /L, 38.99±2.49g/L,while the control group was 69.66±3.41g/L, 36.89±3.34g/L.The serum protein loss amount of rapid rehabilitation was less than the control group; the difference is statistically significant(p<0.05).3. During the rapid treatment of hospitalized patients in the FTS groupsatisfaction was 93.3%(28/30) while in the control group was 71.8%(23/32).Rapid rehabilitation of patients treatment satisfaction was significantly higher,the difference was statistically significant(P <0.05).Conclusions:1. Fast track surgery used in colorectal surgery perioperative patients can significantly shorten the time of the recovery of gastrointestinal function, greatly reducing postoperative pain; the average time of hospital stay was significantly shorter, and it can reduce medical costs without increasing anastomotic fistula, incision infection, postoperative complications such as intestinal obstruction.2. Fast track surgery of colorectal cancer perioperative application can significantly reduce postoperative inflammation to patients and during the operation the loss of serum proteins is less; postoperative nutritional status of patients significantly improves as well as the high patients’ satisfaction.3. Fast track surgery for colorectal cancer in the perioperative period is safe and effective.4. Fast track surgery at the local hospital in colorectal cancer surgery is safe and feasible, which can be widely used.
Keywords/Search Tags:Fast-track surgery, Colorectalsurgery, Perioperation, Mec hanical bowel preparation
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