Clinical Observation Of Xingnaojing Injection In The Treatment Of Dengue Fever

ObjectiveThe study is to investigate the effects of Xingnaojing Injection on patients with dengue fever (Wei Qi disease syndrome). Through its influences on the TCM syndrome integral, antifebrile time, white blood cell and countplatelet count, to evaluate efficacy and safety of Xingnaojing injection and aim to provide a clinical reference for the treatment of dengue fever with Chinese Medicine.Methods54 cases of dengue fever(Wei Qi disease syndrome)were selected in accordance with the inclusion criteria as the object of study randomly divided into treatment group and control group,27 cases in each group. The control group was given general symptomatic support therapy, including cool, intravenous and oral rehydration, hemostatic and protecting stomach, etc. The treatment group was treated with Xingnaojing injection 20ml with 0.9% sodium chloride 5% glucose 250ml diluted intravenous drip on the basis of the control group, once a day, a course of 5 days. Observation index:TCM syndrome integral.antifebrile time, white blood cell and countplatelet count, etc. Comparing the treatment group and control group before and after treatment and the differences between control group and treatment way.Results1. There were no statistically significant differences in the age, sex, skin rash appearance, liver and kidney function before treatment in the two groups of patients(P>0.05), with comparability.2.There were no significant differences in the TCM syndrome integral between the two groups before treatment(P>0.05);Symptoms were improved significantly after treatment, the difference was statistically significant (P<0.05);The treatment group Compared with control group after treatment, the difference was statistically significant(P<0.05).3.The treatment group was shorter than the control group in the time of fever disappearance, the difference was statistically significant(P<0.05).4. The comparison of white blood cell count between the two groups before treatment, there was no statistically significant difference(P>0.05); Compared with before treatment, the white blood cell counts increase significantly in two groups after treatment, the difference was statistically significant(P<0.05);The treatment group Compared with control group after treatment, the difference was statistically significant(P<0.05).5. The comparison of the platelet count between the two groups before treatment, there was no statistically significant difference (P>0.05); Compared with before treatment, the platelet count increase significantly in treatment group,the difference was statistically significant(P<0.05); Compared with before treatment, the platelet count ascension is not obvious in the control groupafter treatment, and there was no statistically significant difference(P<0.05);Compared with control group after treatment, there was no statistically significant difference in the treatment group(P<0.05)Conclusion1. The two groups can improve the clinical symptoms of patients, but the treatment group symptoms improved more significantly.2. Xingnaojing injection can quickly cooling in patients with dengue fever (Wei Qi disease syndrome), shorten the cooling time is better than the control group.3. The treatment group was higher in white blood cell count, platelet count, but the average white blood cell count,platelet count were higher than the control group after treatment, The data of the two indexes after treatment of the two groups did not exceed the reference value range.4. Xingnaojing injection for the treatment of dengue fever has better security.