The Clinical Research Of TCRA Combined With Zi Yin Huo Xue Decotion And Estrogen-progesterone Sequential Therapy For The Intrauterine Adhesions

Objective:Choose Zi Yin Huo Xue decotion combined with Estrogen-progesterone sequential in the treatment of patients of intrauterine adhesions after surgery.Discuss the clinical effects by observing the recovery of menstrual quantity,symptoms of traditional Chinese medicine and the form and thickness of endometrial,aimed at intervening it as early as possible after surgery, asissting in the recovery of menstrual quantity and endometrial function, reducing the recurrence rate and improving the pregnancy rates.Methods:In March 2015 to March 2016 in Chinese medicine hospital of jiangsu province,35 patients of hysteroscopic diagnosis of mild to moderate who took the adhesion separation surgery, are randomly divided into treatment group and control group with 15 cases in each group,4 cases of loss by midway lost to follow-up,1 cases had removed for preoperative six is not in the normal range of sex hormone, and 30 cases of actual were done. The treatment group were treated with Zi Yin Huo Xue decotion combined with progynova and dydrogesterone, the control group were treated with only progynova and dydrogesterone. The purpose is to observe the recovery of menstrual quantity,TCM Syndromes,the form and thickness of endometrial and the IUA degree after the therapy lasting three cycle and taking out the ring.Results:(1)Through the comparison between before and after the therapy,it conclueds that all the symptoms are improved in two groups after treatment. P<0.05 in all the comparison of scores,it has a statistically significant difference in curative effect.(2)Through the comparison between the treatment group and control group,it concludes that the curative effect of the former is superior to the latter in most cases.1)The treatment group were significantly better than the control group in the improvement of menstrual volume and the accompanied syndromes of TCM, P<0.05, has a statistically significant difference.2) There are no significant difference between the two groups in the thickness of endometrial,P>0.05.But the thickness of the mean of treatment group is greater than control group after treatment.3)There are no significant difference between the two groups in the recovery of intrauterine adhesions.But the score of treatment group is lower than control group after treatment.Moreover,the recurrence rate of fomer(13.3%) is lower than the latter(26.7%).(3)The total effect:The treatment group:clinical control 7 cases, accounting for 46.7%; effective 7 cases, accounting for 46.7%;invalid 1 cases, accounting for 6.6%; total effective rate is 93.4%.The control group:clinical control 2 cases, accounting for 13.3%; effective 10 cases, accounting for 66.7%;invalid 3 cases, accounting for 20.0%; total effective rate is 80.0%. The treatment group is better than the control group in the total effect.Conclusion:Zi Yin Huo Xue decotion combined with Estrogen-progesterone sequential in the treatment of patients of intrauterine adhesions after surgery can improve the menstrual volume and TCM syndromes significantly. The clinical effect is better than using western medicine alone.