Endoscopic Ultrasonography T And N Staging Of Rectal Cancer After Neoadjuvant Therapy Diagnostic Accuracy Studies

Objective:Through clinical observation, this study explore endoscopic ultrasonography T and N staging of rectal cancer after neoadjuvant therapy diagnostic accuracy, so as to provide reliable basis for clinical treatment optionsMethods:Choose between January 2010 and June 2010, our hospital by electronic colonoscopy and pathology diagnosis of preoperative neoadjuvant therapy and surgical resection for rectal cancer in parallel,a total of 36 cases of male 23 cases, 13 cases of female, of all inspectors are first prepared intestinal after all e. electronic endoscopy, found after rectal lesions, endoscopic biopsy for pathological examination diagnosis, according to the standardized guidelines for rectal cancer after(a)(2013), the implementation of neoadjuvant chemoradiation, namely chemotherapy regimens: on the basis of 5- FU of chemotherapy regimens, mainly is the joint oxaliplatin into 5- FU solution, treatment time 2 ~ 3 months.Radiotherapy plan: the traditional auxiliary radiotherapy plan, usually a total dose of 40-60 Gy, divide dose for 1.8 2 Gy,radiation five weeks in a row, 5-10 weeks after completion of radiotherapy again fully prepared the gut,endoscopic ultrasonography examination.Endoscopic ultrasonography to choose Japan Olympus UM2000 ring and small ultrasonic probe, the probe frequency range selection for 12 to 20 MHZ, both in sterile water for injection invasion bubble downward ultrasound scan, record the extent of erosion(T) and the surrounding lymph nodes(N).Above all of the patients in perfecting the endoscopic ultrasonography examination after surgery, record postoperative pathological T and N stage, finally carries on the analysis judgement.With endoscopic ultrasonography findings and patients after surgical removal of the histologic examination were compared, and it is a standard with postoperative pathological histology, endoscopic ultrasonography after neoadjuvant therapy evaluation of the accuracy of T and N stage.Results:Endoscopic ultrasonography in the diagnosis of 36 cases of rectal cancer after neoadjuvant therapy T staging accuracy was 38.9%, the accuracy of the diagnosis of local lymph node N is 55.6%,sensitivity 50%, 7/14) 59.1%(13/22)Conclusions:Endoscopic ultrasonography T and N staging of rectal cancer after neoadjuvant therapy diagnostic accuracy remains to be further improved.