Artificial Movement In Rats Induced By Different Temperatures Cross Experimental Study Of The Pattern Of Muscle Syndrome Dissolution

Background:Rhabdomyolysis rhabdomyolysis syndrome is a medical emergency, with a complex etiology, sudden onset, complex diagnostic procedures that can lead to clinical features of multiple complications. In recent years, its presence is gradually coming into view, appeared in a variety of medical events in the news. By the2010Nanjing crayfish event, the2012event and binge eating seafood event pushups understanding rhabdomyolysis is evident. With the improvement of people’s living standards, a single creature comforts have been difficult to meet the needs of modern society, people will live up to shift the focus to the spirit of enjoyment, looking to enjoy the material and spiritual balance, therefore, to seek personal spiritual stimulation of extreme sports, more and more sports enthusiasts pro-Lai. Corresponding rock climbing, mountaineering, skiing, surfing and extreme sports related to the outside temperature, leading to rhabdomyolysis cases is also increasing. Improvement of living standards, will inevitably lead to the accelerated pace of life, work pressure will suddenly increase, leading to prolonged high-temperature operation RM events have also been reported.Objective:With the social progress and accelerated pace of life, people shift in values, a single transition from the pursuit of material wealth of material and spiritual double enjoyment, more and more people began to participate in the process of diversification of sports, inevitable "environmental incident" consequential. Therefore, this experiment at different temperatures were measured in rats swim analysis of the indicators, designed to further investigate the mechanism of temperature-induced rhabdomyolysis syndrome, resulting in movement of populations for different events rhabdomyolysis environmental factors to provide a reference. Given these cause, we have reason to believe that the outside temperature and the occurrence of rhabdomyolysis intrinsically linked. In this study, the basis of previous studies for rhabdomyolysis above, focusing on the temperature factor for a long time by the mechanism of high-intensity exercise occurs RM, RM strive to study the pathogenesis of growth factors add ink pen.Methods:This study selected40SD rats after feeding in their natural environment adaptability week, the rats were randomly divided into four groups:normal control group, the low exercise group swimming, swimming group at room temperature, heat swimming group. In addition to the experimental group started the other three groups adaptive swimming training once a day, the time increments from5minutes to30minutes, then began a formal swimming.50cm x50cm x50cm training conducted sink, static depth40cm, once started swimming every morning. The experiment was conducted3months, during which rats were measured immediately after every experiment rectal temperature, body weight was measured once every3days, after3months for the three groups of rats sacrificed immediately after exhaustive exercise, peritoneal venous blood of kidney and indicators gastrocnemius organizations rat blood creatine kinase (CK) levels, serum creatinine (SCR) level, myoglobin (MB) levels, muscle fine organizations.Results:(1) when the core temperature of hot and cold environment movement in rats with changes in the external environment changes, the ambient temperature affect the body’s core temperature by increasing the degree of rhabdomyolysis syndrome.(2) hot and cold environment than the normal temperature environment, the more impact CK and MB level, in other words, high-intensity exercise in a cold environment for a long time, for more serious damage to muscle tissue. Of course, large temperature environments intensity exercise the same muscle tissue damage.(3) serum creatinine level indicates the degree of kidney damage, extreme environments significantly elevated serum creatinine movement, the environmental movement, said the cold damage the kidneys, may cause acute renal failure.(4) Through the analysis of various physiological and biochemical indicators of operating in extreme environments will cause serious damage to the body. Performance in terms of damage to the core temperature changes, organ tissue.All test indicators, data were processed by statistical methods.Conclusions:1、 low-temperature environment during exercise in rats core temperature will drop, blood ck, serum creatinine, myoglobin levels higher than the normal temperature group, indicating that the movement of the body temperature environment in muscle tissue damage and renal function.2、a sharp rise in high-temperature environments ck, serum creatinine, myoglobin indicators compared with other groups of rats blood, indicating that the thermal environment in the body from exercise-induced rhabdomyolysis syndrome highest probability.3、groups of rats at room temperature in high-intensity exercise in blood ck, serum creatinine, myoglobin levels higher than the control group, indicating that at room temperature, high-intensity exercise will also cause damage, but a lesser degree of injury.4、induced rhabdomyolysis syndrome produce large intensity exercise dominant, but in extreme environments Exacerbate rhabdomyolysis syndrome generation.