Study On Surface Modification Methods Of Nerve Stimulation Electrode

As implantable biomedical electronic technology develops, electrical stimulation in specific parts of the body by a certain size microelectrodes can treat diseases that conventional drugs and surgery fail to cure, such as age-related macular(ARM), facial paralysis, and retinitis pigmentosa(RP). However, the nerve stimulation electrodes in vivo tissue environment will age gradually after a long period and problems like the reduced effectiveness of microelectrodes and reliability caused by the dramatic increase in the electrode impedance value and the electrode surface of the package occur. Since surface modification of the microelectrode can improve the electrical efficiency and reliability, it has become in recent years a research focus.Firstly, the site of stimulation electrodes 512 processing methods was investigated in this paper. Having conducted surface modification on the platinum electrode of 200 ?m, a comparative analysis on the electrical stability and reliability of composite coatings between individual plating platinum gray, gray and iridium oxide, and platinum iridium oxide was studied. The main conclusions are as follows:(1) In order to meet the needs of a new generation of high-resolution process artificial retina, the processing technic of implantable electrode array of 512 stimulating sites which aims at the design and production of flexible retinal stimulation microelectrodes was studied.(2) The surface modification of 200 ?m diameter platinum electrode. By Gamry600 electrochemical workstation, the electrochemical test and analysis on the surface impedance of nerve stimulation microelectrode were studied. Tested by linear voltage sweep and extracorporeal cyclic voltammetry, the optimal potential window that best fits for electroplating and stability of microelectrode in vitro solution system were confirmed. The change in resistance value observed in the ultrasonic stirring experiment indicates the stability of the surface combination of the modifier and nerve stimulation microelectrode. The passive accelerated aging test simulates whether the electrode in the body loses effect after a period of time and it helps save time and lower economic cost.