The New Design?synthesis Of ?-Lactone With Special Aroma Characteristics And Application

Flavor is the basis of compound flavor,fragrance performance is more dependent on the combination of science and art of all kinds of spices,however,with the development of perfume fragrance industry,natural flavor varieties and production cannot meet the needs of various flavored product,therefore,the synthesis of new type of raw material is imperative.Esters of spices in the spices industry occupies a special important position,carboxylic acid esters of spices varieties accounted for about 20%of the total number of spices,and lactone class spices varieties is less than 5%.The lactone class spices are ?-lactone,?-lactone and large ring lactone,lactone class flavor compounds with fruit milk incense and musk,mostly by flavouring workers love and attention,widely used in cosmetic fragrance and flavor.But these existing lactone class spices cannot satisfy the need and deployment of diversity and creative fragrance development needs,in particular,some with floral bouquet or honey aroma lactone class spices is relatively small,and the essence of innovation and improvement of quality is becoming more and more dependent on new varieties of synthetic spices,this paper aims to design new synthetic ?-lactone compounds,complement and extend the ester fragrance raw material varieties,for providing new ways and means of an increasing in the number of varieties and improve the quality of synthetic spices.On the basis of literature review,this paper design and synthesis of the four kinds of ?-lactone compounds,and its application in flavors on the exploration and research,the concrete content is as follows:The first part:in five the eight carbon atoms amyl alcohol,hexanol,heptanol,octanol fatty alcohol and acrylic acid as raw materials,respectively,under the action of the methyl benzene sulfonic acid catalysis using toluene as solvent,reaction temperature 110? reflux system 8h four intermediates in the synthesis.Then respectively using intermediates and 1-pyrrolidine-1-cyclohexene in chlorine peroxide between benzoic acid and sodium hydrogen phosphate under the catalysis of using dichloromethane as solvent,reaction temperature to room temperature under the protection of nitrogen the final synthesis of four new ?-lactone compound spices,rate between 6%and 8%,and the structures were confirmed by 1H NMR and 13C NMR.These four new ?-lactone compounds identified aroma have rice wine of alcohol and tobacco,wine aroma fragrance,think that is a kind of be flavourists can be applied to chemical essence,edible flavor and tobacco flavour pleasant fragrance raw materials.At the same time,the research results show that with the increase of the number of carbon atoms,their aroma is weakened.The second part:These four new s-lactone compounds apply to the application of flavouring,deployment of rose essential oil,and with the same amount instead of wine aroma composition of raw materials,recycling electronic nose with aromas of analysis,electronic nose to distinguish index is 94,shows that electronic nose experiment well distinguish the products overall properties of volatile components.It can also be concluded from the DFA and Radar that these four new ?-lactone compounds can perfectly instead of wine aroma composition of raw materials,and make the aroma of rose essence is more natural and fruity.The third part:the deployment of rose essential oil of sensory evaluation experiment,by sorting inspection method and paired comparison test data analysis can be concluded in this paper,the synthesis of new s-lactone compounds in the performance of deployment of rose essential oil fragrance is the best,because this kind of rose essential oil fragrance performance the most natural and harmonious.