Migration Regularity Of Phthalate In Plastic Food Container

Phthalate, a primary plasticizer, is an essential compound for food plastic package making. It is well known that phthalate is toxic and harmful to body health, which induce teratogenesis, carcinogenesis and reproduction toxicity due to its accumulation. The current study investigated the migration of phthalate from food container to simulation solution under different conditions and established migration model, provides the basis for food container in the use of safety evaluation.Method for phthalate extraction from food container using ASE300 instrument was established. Optimization test demonstrated that the optimal solvent was n-hexane, optimal temperature was 70? and optimal time was 3 min. Quantitative detection method was established according to GC-MS method described innational standard, with detection limit(DL) of 2 ng/g and quantitative limit (QL) of 6.7 ng/g. Dibutylphthalate (DBP) and disobutylphthalate (DIBP) were two primary phthalates detected in four commercially available food containers. Food container made from polypropylene (PP) has the maximum concentrations.with values of 1.5 mg/L and 2.4 ,g/L,respectively. Bycontrast, the other three containers showed less phthalate amount of 0.3 mg/L for DIBP and 1.6 mg/L for DBP,respectively.The phthalate levels in four different types of food containers varied within the permissible scope defined by the National Standard, indicating a relatively lower security r-isk.Food container was further used to investigate the migration of dibLutyl phthalate and diisobutylphthalate in four simulation solution of distilled water. 3% acetic acid, 10%ethanol and isooctane under different temperature of 4?, 25? 40? and 60?. The results demonstrated that migration of phthalate was greatly influenced by migration solution type and the maximum migration amount was noted in isooctane due to the lipophilicity of phthalate. Migration amount was found to be indirect proportionto immersing temperature.Linear fitting of DBP and DIBP migration amount was then performed according to Crank theory and first-order kinetic equation. The migration equations obtained under different immersing temperature and simulation solutions were all accorded with first-order kinetic equation. It is concluded that the rate constant (k1) and initial release rate (V0) of phthalate in different simulation solution were significantly different. Lower polarity of simulation solution and higher immersing temperature came with the higher values of k1 and V0.