Fluid-solid Coupled Analysis Of Hemodynamics For Vena Cava Filter

Pulmonary embolism(PE)is one of the most common cardiovascular disease,and in its treatment,vena cava filter implantation have attracted the most attention.At present,the common filter can be divided into Permanent filter and Retrievable filter,and the complications of the both kinds of filters can not be ignored.New convertible vena cava filters as a study object,can not only avoid these complications,and can be very good to capture thrombus.Fluid-structure coupling of vena cava blood vessels with 3 different filtering unit structure,3 different diameter of new filters and 2 types of commonly used Retrievable filters were simulated numerically by computer simulation software.And then their hemodynamic characteristics,filtration efficiency and fluid-structure interaction were comparatively analyzed.Specific research contents and results are as follows:(1)3 different filtering unit structure of filter models were established,which are L style,S style and W style filter respectively,and their hemodynamic characteristics,filtration efficiency and fluid-structure interaction were comparatively analyzed under the condition of different thrombus diameter and content.The results showed that: the difference of filter's filtering unit structure has no apparent effect on hemodynamic.With the increasing of thrombus' s diameter and content,the hemodynamic factors show the decreasing tendency.This means that the bigger diameter and the more content of thrombus,the more easy to cause thrombosis and insufficient blood supply at the downstream,and even cause vena cava obstruction.When it comes to filtration efficiency,S style filter and W style filter show better performance.the bigger diameter and the more content of thrombus,the better filtration efficiency.When it comes to fluid-structure interaction analysis,the fluid-structure coupling interaction of blood flow respectively with vessels and filters are basically identical under the condition of thrombus different diameter and content.The difference of filtering unit structure has a certain effect on it,but not dramatically.(2)3 different diameter of filter models were established,which are 24 mm,28mm,and32 mm respectively,and their hemodynamic characteristics,filtration efficiency and fluid-structure interaction were comparatively analyzed under the condition of different thrombus diameter and content.The results showed that: When it comes to hemodynamic,the increasing of filter's diameter cause the decreasing tendency of hemodynamic factors.When it comes to filtration efficiency,L-32 filter show better performance on it.When it comes to fluid-structure interaction analysis,the fluid-structure coupling interactions ofblood flow respectively with vessels and filters have no significant changes under the condition of filters' different diameter.(3)2 different kinds of Retrievable filter models were established,which are Option(Opt)and Celect(Cel)filter respectively,and their hemodynamic characteristics,filtration efficiency and fluid-structure interaction were analyzed and compared with L-32 filter under the condition of different thrombus diameter and content.The results showed that:When it comes to hemodynamic,Opt filter has minimal effect on it,L-filter is in the middle,Cel filter is the greatest.When it comes to filtration efficiency,Cel filter and Opt filter's performance are better.When it comes to fluid-structure interaction analysis,the fluid-structure coupling interactions of blood flow respectively with vessels and filters have no significant changes.Filters with different filtering unit structure,different diameter and different types were analyzed in hemodynamic and fluid-structure coupling interaction with the use of fluid-solid coupling calculation method.This research provided important reference to the development of vena cava filters and clinical application.