Research On Piezoelectric Micropump For Insulin Delivery

With the increased prevalence of diabetes,the patient wearing a portable insulin pump to maintain the body's normal amount of insulin demand continues to increase.In the face of the high price of the traditional plunger insulin pumps and other issues,the development of piezoelectric insulin pumps can be exempted from the use of micro-stepper motor and precision transmission device,which saves the purchase cost of the insulin pump and is conducive to the rapid spread of products.At the same time,the driving principle of the insulin pump is very different from that of the traditional plunger insulin pump.It uses the deformation of the piezoelectric material driven by the positive and negative voltage to drive the liquid flow.There is no transmission components in the pump,so it has the potential to be miniaturization and has a huge market value.This paper makes the design of the pump body of the piezoelectric pump used for insulin injection a priority.In order to determine the structure parameters of piezoelectric oscillator and cantilever check valve,on the basis of theoretical calculation,the simulation model of piezoelectric oscillator and cantilever valve is established.By means of finite element simulation,the motion characteristics of the components are analyzed,and the important parameters such as natural frequencies and vibration amplitudes of the components are calculated.Finally,the original parameters of the components are determined by optimizing the design analysis.In order to further study the interaction between the cantilever valve and the liquid in the working process,and to design the micro-pump cavity flow channel,the fluid region involved in the piezoelectric pump is modeled in this paper.Through the joint analysis of ANSYS Workbench and Fluent,the two-way solid-liquid coupling analysis method is introduced into the design of the valve piezoelectric micropump.The valve shape design is refined and the fit size between the valve and the pump body as well as installation gap and outlet flow channel are determined.And the single-cavity and double-cavity micropump structures are designed in combination with the above analysis.In order to meet the demands of piezoelectric micro pump design,a piezoelectric pump drive power is designed.A drive voltage source is formed by the single-chip microcomputer controlling the output frequency and the back-end is adjusted by the complementary amplifying circuit and the driving power supply circuit board is produced.The components of piezoelectric insulin micropump are tested in small batch,the experimental prototype is assembled,and the mass production process is studied.A performance test is conducted on the prototype.The dimension parameters of the piezoelectric pump are adjusted by repeated experiments to find out the best operating point of the piezoelectric micropump.And the minimum resolution of the flow,pressure and flow rate of the piezoelectric pump is measured at the same time.And the development of portable piezoelectric insulin pump is explored macroscopically.