Diagnostic Value Of TI-RADS And VTQ In Thyroid Nodules

Objective: To expand the diagnosis strategy for thyroid nodule through comparing the value of thyroid imaging reporting and data system(TI-RADS)and touch tissues quantification(VTQ)in the diagnosis of benign or malignant thyroid nodules.Methods : A total of 51 patients with 93 thyroid nodules were performed of conventional ultrasonography collected between September 2015 to January 2016 in The First Hospital Of Wannan Medical College.The 93 nodules were classified with TI-RADS standard.The shear wave velocities(SWV)of thevirtual touch tissue quantification(VTQ).Taking pathological results as golden standard,receiver operating characteristic(ROC)was plotted analyzing the diagnostic value of virtual tiuch tissue quantication.Compare the effectiveness of two methods in differential diagnosis of thyroid nodules.Results:(1)The pathological results of the 93 nodules were as follows: 61 benign nodules,32 malignant nodules.(2)The differences in thyroid nodular shape,margin,internal echo,calcification,and skin growth,rear echo characteristics and cervical lymph node metastasis by TI-RADS diagnostic criteria in the differential diagnosis of benign and malignant nodules were statistically significant(P < 0.05),but blood differences in benign and malignant thyroid nodules has no statistical significance(P > 0.05).(3)The sensitivity,specificity,accuracy,positive predictive value and negative predictive value of TI-RADS diagnostic criteria in the diagnosis of benign and malignant thyroid nodules was respectively 90.63%,88.52%,89.25%,80.56%,94.74%.The sensitivity,specificity,accuracy,positive predictive value and negative predictive value of VTQ was respectively 87.50%、95.08%、92.47%、90.30%、93.55%.Both have high sensitivity,specificity and accuracy,the difference was not statistically significant(P> 0.05).(4)The average VTQ value in malignant thyroid nodules is(2.65 + 0.96)m/s;the average value of VTQ value in benign thyroid nodules is(1.88 + 0.87)m/s;the average value of VTQ is(1.88 + 0.87)m/s in normal thyroid tissue around the nodules.Value of VTQ of malignant thyroid nodules was significantly higher than that in benign thyroid nodules and nodules surrounding normal thyroid tissue,the difference has statistical significance(P < 0.01);and benign thyroid nodules of VTQ value compared with the surrounding thyroid tissue of the nodules also has statistical significance(P < 0.05).(5)When the VTQ cut-off point is the 2.544m/s and VTQ technique in the diagnosis of thyroid benign and malignant nodules has the highest sensitivity,specificity,and has good value in differential diagnosis.(6)The area of ROC for TI-RADS,VTQ and TI-RADS combining VTQ was respectively 0.896,0.913 and 0.918.That two kinds of methods and the two combined use of their respective for the differential diagnosis of thyroid nodules have higher value,but they are used on the diagnosis efficiency has no obvious statistical significance difference.Conclusion: TI-RADS diagnostic criteria differential diagnosis of benign and malignant thyroid nodules diagnosis with high sensitivity,can be described in terms of a unified and standardized thyroid between doctors,physicians and clinicians for imaging image communication,which can avoid the subjectivity of physician diagnosis.The average value of VTQ of thyroid nodule provide a more objective analysis quantitative determination,it can be used as an effective index in differential diagnosis of benign and malignant thyroid nodules with high specificity and accuracy.When the VTQ cut-off point is the 2.544m/s and VTQ technique in the diagnosis of thyroid benign and malignant nodules had high specificity.It can be used as an new important diagnosis supplementary means to provide help in clinic for diagnosis of thyroid nodules,and it should be on the basis of the TI-RADS classification diagnosis standard,can not rely too much on and overestimate the value of VTQ.The combination of the two methods can provide more information on the different aspects of the differential diagnosis of some difficult thyroid nodules,and it has some auxiliary diagnostic value.