Clinical Observation Of JieYu AnShen Prescription Of Insomnia With Anxiety State (Stagnation Of The Fire-type)

Objective:To observe Atagnation Treatment of insomnia with anxiety state (liver-fire type) clinical efficacy, by comparing the Pittsburgh Sleep Index Scale, the Hamilton Anxiety Scale, insomnia TCM syndrome score scores, confirming its clinical effectiveness, rich Chinese medicine treatment of insomnia means and methods, to provide a reasonable, comprehensive clinical scientific basis.Methods:This study collected the First Affiliated Hospital of Henan University of Chinese Medicine encephalopathy outpatients April 2015 to December 2015 or hospitalization choose through inclusion criteria, exclusion criteria screening of 56 patients were randomly grouped a group for the treatment group (Atagnation party group) and the other group was the control group (alprazolam), two groups were given cognitive behavioral therapy, on this basis, the treatment group received Atagnation Party (Chaihu 10 grams 3 grams berberine 20 grams Angelica 15 grams peony Paeonia 15 grams gardenia 10 grams Caulis 15 grams of mint 6 grams of Semen 15 grams 6 grams of licorice, selected granules) treatment, control group was given alprazolam treatment, treatment period of 4 weeks were observed, recorded the first four weeks after the clinical efficacy of two groups of patients, as well as before and after treatment Pittsburgh sleep index scale, the Hamilton anxiety scale, insomnia TCM syndrome score score changes and adverse reactions.Results:The two groups were observed after treatment of clinical data, statistical analysis the following conclusions:Treatment:Atagnation party group, the total efficiency of 89.29%, alprazolam group, the total efficiency of 67.86%, the two groups showed a significant difference in treatment effect (P<0.05), prompted two drugs for the treatment of insomnia with anxiety They are valid, but the effects Atagnation party than alprazolam.Pittsburgh Sleep Quality Index Scale (PSQI):After treatment, PSQI scores were all significant changes before treatment, but Atagnation party group than alprazolam integration can reduce significantly superior than alprazolam group.Hamilton Anxiety Scale:After treatment, PSQI scores were all significant changes before and after treatment by statistical analysis, Atagnation party group scores were significantly better than the alprazolam group, can reduce the points.Insomnia Syndrome Rating:After treatment, Atagnation party group points significantly lower than alprazolam group, statistical analysis, significantly better than the alprazolam group.Safety:the control group during the treatment One patient with dizziness, after spontaneous remission, I no obvious adverse reactions. Three conventional, liver and kidney function, ECG findings comparing two groups of patients before and after treatment showed no significant change.Conclusion:Resolve depression nerves with estazolam can improve insomnia patients with anxiety state (liver fire type) with PSQI, HAMA scores, suggests that there are exact clinical curative effect, statistical analysis showed that resolve depression nerves in improving sleep quality and alleviate the symptoms of liver depression, fire is better than that of estazolam, may be resolve depression than estazolam more nerves can improve the patients'anxiety state.