Clinical Observation On Jieyu Anshen Decoction In Treating Insomnia With Anxiety State(liver Depression And Fire Type)

ObjectiveThe 21 st century is a century of rapid development in all walks of life.Whether it is economic development or social change,everyone in this era is facing enormous psychological pressure.The incidence of insomnia,anxiety and depression is high in this era.Although traditional hypnotic drugs have a certain effect on the treatment of insomnia,they have the disadvantages of being addicted and prone to repeated after taking medicine for a long time.Many patients with insomnia have a certain psychological burden in the process of taking medicine,so traditional hypnotic drugs have not Fundamentally solve the insomnia trouble of patients.In this study,through a randomized controlled trial,observe the clinical efficacy of Jieyu Anshen Formula in treating insomnia with anxiety(liver depression and fire type),analyze the characteristics of Jieyu Anshen Formula and discuss its mechanism of action,which is a clinical liver depression and fire type Provide reference for the treatment of insomnia.MethodsThe sample for this study was from insomniacs who visited theDepartment of Neurology(Huayuanshan Campus)of Hubei Provincial Hospital of Traditional Chinese Medicine from March 2018 to October2019.Among them,60 patients with insomnia suspected of having anxiety were selected by the Chinese medicine diagnosis of liver depression and fire type and determined by Hamilton Anxiety Scale.They were randomly divided into an experimental group and a control group using a random number table method,with 30 cases in each group.The general information(including gender,age,course of disease,PSQI,HAMA,scores of insomnia TCM syndrome scale)of the two groups of patients were not statistically different(P> 0.05),and were comparable.The experimental group used Jieyu Anshenfang(Danggui10g,Baishao 10 g,Bupleurum 10 g,Jiao Gardenia 10 g,Peony Skin 10 g,Hehuan Skin 10 g,Shouwuteng 10 g,Poria 15 g,Dangshen 10 g,Tangerine10g,Fried Atractylodes 10 g,10g of ginger,6g of mint,10 g of lily,10 g of vinegar and 10 g of licorice root,3g)intervention,taking400 ml boiled water,one dose daily,200 ml each morning and evening;the control group was given zopiclone tablets,oral,every night Half slice.Both courses of treatment were four weeks.Four weeks later,SPSS software was used to statistically process the relevant data of PSQI,HAMA,and TCM syndrome scores before and after treatment to evaluate the clinical efficacy of Jieyu Anshen Recipe.Results(1)Comparison of general data(gender,age,course of disease)before and after treatment showed that the data of the two groups were comparable(P> 0.05)(2)The scores of the PSQI scale before and after treatment showed that the data of the two groups were comparable(P> 0.05)After four weeks of treatment,the sleep status of the patients in the experimental group and the control group wereimproved(P <0.05);compared between the groups,the experimental group was more effective than the control group(P <0.05).(3)The HAMA scale scores of the two groups before and after treatment showed that the data of the two groups were comparable(P> 0.05);after four weeks of treatment,the anxiety status of the two groups of patients was improved;compared between the groups,the experimental group was more effective than the control group it is good.(4)The scores of insomnia TCM syndromes showed that the data of the two groups were comparable(P> 0.05);after four weeks of treatment,the TCM syndrome scores of the two groups of patients decreased(P <0.05);the comparison between the groups and the experimental group was more than the control The effect of the group was more significant(P <0.05).(5)Comparison of clinical efficacy after treatment showed that the total effective rate of the experimental group was 83.3%,and the total effective rate of the control group was 66.7%.The total clinical effective rate of the experimental group was better than that of the control group,and the difference was statistically significant(P <0.05).(6)The safety indicators of the two groups showed that there were no obvious abnormalities in the vital signs,routine hematuria,electrocardiogram,liver and kidney functions of the two groups of patients before and after treatment,and no obvious adverse reactions during the treatment.ConclusionThe clinical curative effect of Jieyu Anshen Recipe in treating insomnia with anxiety(liver stagnation and fire type)is superior to that of traditional western medicine treatment,and there are no obvious adverse reactions in the course of treatment.