The Clinical Therapeutic Effect Of Ginger-partitioned Moxibustion Combined With Wen Yang Zhu Shui Gao Acupoint Application On Hepatic Cirrhosis Ascites

Objective: To objectively evaluate the clinical curative effect and safety of the method of ginger-partitioned moxibustion combined with Wen Yang Zhu Shui Gao acupoint application used for treating hepatic cirrhosis ascites,clear its function advantage,and initially analyze its mechanism,to provide the effevtive basis for the clinical application of this method,and to provide the beneficial reference for exploring new safe and effective external therapy of traditional Chinese medicine.Methods: Selecting 60 cases who had been diagnosed with spleen and kidney yang deficiency type of patients with hepatic cirrhosis ascites,which met the inclusion criteria and exclusion criteria for the study.They were randomly divided into treatment group and control group according to the order of admission and principles of random number table,each group had 30 patients.Both groups took different treatment measures,the control group was treated with routine western medicine and Shenfu Xiangui Granules,the treatment group added ginger-partitioned moxibustion combined with Wen Yang Zhu Shui Gao acupoint application basing on the treatment of the control group.A total of two courses,a course of 10 days,followed-up of 3 months.Then record the changes of symptom scores,the abdominal perimeter,the weight,the urinary volume for twenty four hours,the color doppler ultrasound(the depth of ascites),the liver function(TBIL,ALT,AST,ALB),renal function(BUN,Cr),electrocardiogram(K~+,Na~+)and the occurrence of adverse reactions,observe the clinical curative effect of the two groups and syndromes curative effect,ultimately make the therapeutic evaluation with statistical azlalysis.During the study,1 case in the treatment group fell off,and 2 cases in the control group fell off,so the actual number into the group for the treatment group 29 cases,28 cases in the control group.Results: 1.The total curative effect of the treatment group was 93.10%;the total curative effect of the control group was 71.43%.Compared the two groups,the difference has statistically significant(P<0.05),which showed that the therapeutic effect of the treatment group was better than that of the control group.2.After treatment the symptom scores of two groups were significantly lower than before treatment,and the treatment group decreased more significantly,there were significant differences in the variation of symptom scores before and after treatment for both groups(P<0.05);in addition,compared the syndrome effect of two groups,the difference has statistically significant(P<0.05).3.Compared with before treatment,after treatment the abdominal perimeter and weight significantly decreased,the 24-hour urine volume significantly increased,and the treatment group varied more highly than the control group;compared the difference of the abdominal perimeter,the weight,the 24-hour urine volume before and after treatment,it has significant differences for both groups(P<0.05).4.After treatment the main indicators of liver function in two groups were lower than before treatment,and the treatment group improved more significantly than the control group,the difference has statistically significant by statistical analysis(P<0.05).5.The maximum depth of ascites dark areas in two groups after treatment were significantly lower than before treatment,and the treatment group decreased more significantly,there were significant differences in the variations of the depth of ascites before and after treatment for both groups(P<0.05);after treatment the level of ascites in two groups had greatly improved,and the treatment group improved more significantly,there were significant differences by comparison(P<0.05).Conclusion: This study results showed that it was effective for hepatic cirrhosis ascites in both groups,but the curative effect of the treatment group was more remarkable than that of the control group,it can greatly relieve the symptoms and the signs,decrease the abdominal perimeter and weight,increase the 24-hour urine volume,reduce water,improve the level of ascites,resolve ascites effectively,and there were no obvious adverse reactions during and after treatment.It proved that the method of ginger-partitioned moxibustion combined with Wen Yang Zhu Shui Gao acupoint application is an effective treatment on hepatic cirrhosis ascites patients with spleen and kidney yang deficiency syndrome,and it is worth the clinical promoted application.