The Treatment Of Dasuanxiaohuang Pasta For SD Rat AIO And Skin Mechanical Properties

Objective:By observe 1.the treatment of Dasuanxiaohuang Pasta for adhesive intestinal obstruction.2. The transdermal absorption mechanism of Dasuanxiaohuang Pasta Then provides the basis for clinical work.Methods:1.divided 32 rats randomly into 4 groups with the method of serous membrane stripping.We observe the experiment result with the method of X xian ? small intestinal adhesion classification and the structure of small intestine under the microscope.2.Put Dasuanxiaohuang Pasta on the abdomen of Rats,and observe the effects of skin structure in different time(1h ?2h?3h?4h?6h).3.Put the skin into different mixture6 h(ginger juice, vinegar, vegetable oil, blank group),and measuring skin tensile strength.Results:1.The treatment of Dasuanxiaohuang Pasta for SD Rat adhesive intestinal obstruction:The mucous membrane of smallintestine in the model group are seriously injury and have high adhesion classification.But the positive control group and the experimental group all can reduce the degree of injure,have the lower adhesion classification than those model groups of adhesion classification score.2.The transdermal absorption mechanism of Dasuanxiaohuang Pasta:(1) when stick medicine 1 h, the animal does not change significantly activated epidermis and cuticle;Stick medicine 2 h, animal skin stratum corneum began to loose; Stick medicine 3, 4h animal skin epidermis, the stratum corneum is loose; Stick medicine 6 h activity of animal skin epidermis and cuticle and stick medicine 1 h when there is no obvious change. 3.different glue different excipients on the mechanical behavior of skin effect,white vinegar, the strongest.Conclusion:1.Dasuanxiaohuang Pasta can alleviate the degree of intestinal obstruction.all off and the medicine can absorption.2.Attach Dasuanxiaohuang Pasta makes the skin cutin layer falls off osteoporosis,skin intercellular space increased,so it is advantageous to the transdermal absorption.3.Acupoint sticking agent of the natural instinct of vinegar,ginger,vegetable oil can make the skin become loose structure,combination between cells is weaker.