Application Of The Model For End-stage Liver Disease System To Evaluate The Surgical Prognosis Of Patients With Liver Cancer Complicated With Cirrhosis

Objective: To investigate the relationship between the model for end-stage liver disease(MELD) and Child-Turcotte-Pugh(CTP) scoring used in predict the prognosis of patients with liver cancer complicated with cirrhosis.Method: Collected seventy diagnosised and have recived surgical treatment patients with liver cancer complicated with cirrhosis from General Hospital of Ningxia Medical University in 2013-01~2015-09.Results: Thirty-one cases appeared postoperative serious complications, the rate was 30.69%. MELD score was average 13.81±4.72, MELD score in complication group was average 17.65±4.21, MELD score in no-complication group was average 12.11±3.89, the difference between each groups has statistically significant average( P < 0.001). MELD?13, 14?MELD?20 and MELD?21 groups with complication rates were 12.24%( 6/49)? 40.48%( 17/42) and 80.00%( 8/10).The difference between each group has statistically significant( x~2=21.16, P < 0.01). CTP score was average 6.70±1.63. CTP score in complication group was average 7.64±1.72, CTP score in no-complication group was average6.29±1.41, the difference between each groups has statistically significant( F=1.22,t=5.36,P < 0.01). A, B and C groups with complication rates were 16.67%( 9/54)? 43.59%( 17/39) and 62.50%( 5/8). The difference between each groups has statistically significant( x~2=11.85,P < 0.05).Based on Pearson correlation analysis, MELD and CTP were significantly correlated( r=0.963, P < 0.001).Area under the ROC curve was0.819( 95% CI 0.735-0.903) for MELD and 0.756( 95% CI 0.659-0.852) for CTP,The difference between MELD and CTP were not statistically significant( U=0.186, P >0.05).Conclusion: Both MELD and CTP scores can accurately predict the short term prognosis of patients with liver cancer complicated with cirrhosis.