| Objective Impaired glucose regulation(IGR)is a transitional phase and a necessary stage of transition from normal to diabetes(T2DM),which is reversible and takes lifestyle intervention at this stage.It can slow down or even reverse the pre-diabetes to type2 diabetes mellitus Conversion process.However,after the intervention of the lifestyle intervention,the control of blood glucose,blood fat and lifestyle changes,the current less clear.In this study,after the intervention of the participants in the pre-lifestyle intervention,to stop the intervention of the subjects lifestyle,a year later follow-up to observe their blood sugar,blood lipids,body shape,lifestyle changes,with a view to type 2 diabetes Pre-hospital health promotion programs and preventive measures to provide a scientific theoretical basis to ensure the integrity of the overall experiment.Method This study early recruit pre-diabetes,50-65 years after menopause middle-aged and old women on a six-month lifestyle intervention,were randomly divided into control group and exercise intervention group and diet intervention group.Nordic Walking as a way of exercise intervention,movement frequency for 2 ~ 3 times per week,50 ~ 60 minutes every time,exercise intensity is 65% ~ 85% of maximum heart rate.Mainly to give priority to with low carb diet intervention lunch diet intervention,adding dietary fiber.After six months of lifestyle intervention,to a one-year follow-up of subjects,follow-up period is not right to intervene the subjects’ lifestyle,in order to ensure the integrity of experiment,and reduce the loss of subjects,to take a week on the phone,and the door to communicate,organize regular activities,We Chat way to maintain good relationship with subjects such as constructing group.Follow-up tests set subjects,after fasting at 8 PM,seven the next morning OGTT test,obtaining blood indexes,blood tests performed by Shanghai east hospital.Body composition and bone mineral density data subjects in Shanghai sports college sports fitness science museum Dax bone mineral density instrument body composition were determined.Respectively in the control group,exercise and diet group 0 m,6 m and 18 m,comparing the test data,the same set of data analysis in different time period for paired T test analysis method,at the same time take variance test points in different groups of data,p < 0.05 said with a significant difference in statistics.Result1)TG decreased in the control group and the diet group,and the exercise group increased slightly.The triglyceride TG of the three groups decreased after intervention,and the three groups compared the exercise group and the diet LDL-C in the control group was significantly lower than that in the control group(p <0.05),and the expression of LDL-C in the control group was significantly lower than that in the control group(P <0.05),low density lipoprotein LDL-C Follow-up intervention group was lower than the control group.2)The level of fasting blood glucose(FBG)in the intervention group was lower than that in the control group,and the exercise group was the lowest in the three groups.The blood glucose of the postprandial 2h increased by 0M and 6M,but the control group was the highest;the glycosylated hemoglobin Hb A1 c Diet group 0M and 18 M decreased significantly compared to p <0.05,the three groups were the highest in the control group compared with the lowest in the diet group.3)Compared with the three groups,the fat of the lower limbs decreased,and the dietary groups decreased significantly compared with those of thecontrol group(P <0.05),and the ratio of 0M and 18 M in the diet group was significantly lower than that in the control group.The ratio of body fat and fat group was lower than that of the control group(P <0.05).The difference between the two groups was higher than that of the control group(P <0.05)(P <0.05).The body fat ratio of gynoid(hip region)was significantly lower than that of exercise group and diet group(P <0.05),and the body fat group showed a decreasing trend of 0M and 6M,0M and 18 M Compared with the significant decline and p <0.05,diet group 0M and 18 M decreased and p<0.05.4)The upper limbs,lower limbs,trunk,android,gynoid and body mass of the control group showed a significant decrease compared with 0M and 6M.The muscle mass of upper and lower extremities of exercise group and diet group decreased compared with 0M and 6M,and the descending rate was significantly lower than that of control group.Intervention group 18 M trunk,android,gynoid and body muscle mass were increased.5)Bone mineral density group 3 decreased,the control group was the lowest;exercise group 6M and 18 M decreased compared to p <0.05;diet group 0M and 18 M compared,P <0.05,6M and 18 M,P <0.05.6)The exercise frequency and exercise time of exercise group 18 M and 6M decreased slightly but higher than that of control group.A part of the exercise group will still take a Nordic walking exercise.Dietary group 18 M compared with 6M protein intake decreased,fat and carbohydrate intake increased.Diet group in the diet process still focus on coarse grains and dietary fiber intake.Conclude(1)After exercise or diet intervention,the intervention on blood sugar,blood lipid control effect is still there but a downward trend,to continue to maintain a healthy lifestyle;(2)After the intervention of exercise or dietary intervention,the beneficial effect of intervention on muscle loss is still present,the fat content is increased,and the exercise or diet in which the intervention is maintained can have a favorable beneficial effect;(3)Exercise and dietary intervention has a sustained and positive effect on bone density maintenance,but its effect decreases with time;(4)exercise,diet intervention on the subjects of daily life have an impact,the subjects have to improve their daily habits,pay attention to increase the movement and control diet. |
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