Study On The Steamed Notoginseng Powder Of The Preparing Method And The Pharmacological Action Which Was Based On The Theory Of Prepared Notoginseng Can Enrich The Blood And Qi

Panax notoginseng is also called Tianqi, There are different functions between the raw and the processed Panax notoginseng.At present, there have been many studies on Panax notoginseng, and these studies are almost focused on single component or active fraction about the raw, but rarely about the processed. Also there are not all-round enough studies on the pharmacological actions about the function of processed Panax notoginseng. Lack of the studies, the processing method and the quality of Panax notoginseng will be discount. So we need establish a standard processing method of Panax notoginseng, figuring out the processed Panax notoginseng's pharmacological actions are obey the traditional Chinese medicine theory, so that we can make the clinical use of processed Panax notoginseng more reasonable.In the processing procedure, steaming was used. Combined with single-factor experiment orthogonal experiment, the best method was:Panax notoginseng was soaked in water which was 30%weight of the Panax notoginseng for 24h, then steamed for 3h by 110?, then seasoned and pulverized it.In the quality standard research, thin layer (TLC) method is used for qualitative identification of steamed Panax notoginseng. Notoginsenoside R1, ginsenoside Rgi, ginsenoside Rbi, ginsenoside 20(S)-Rg3, ginsenoside 20(R)-Rg3, ginsenoside Rh4 were mensurated by high performance liquid chromatography (HPLC).The differences were figured out between the raw and steamed which was on the base of theory of "prepared notoginseng can enrich the Blood and Qi while the raw one do the opposite." The pharmacological actions researches concluded 7 experiments:the effect on blood loss anemia, anemia caused by chemotherapy (cyclophosphamide, CTX), anemia caused by radiotherapy, alimentary anemia, deficiency of qi, and the effect on Lewis lung cancer, as well as the enhancing efficacy and reducing toxicity of chemotherapy (paclitaxel, pemetrexed disodium). It showed that the steamed Panax notoginseng can do better benefit actions than raw. Steamed Panax notoginseng powder can also inhibition the Lewis lung cancer and have the effect-enhancing and toxicity-reducing efficiency while the raw don'tThe research productionof this resarchhave already been incorporatedin the latest Chinese Herbal quality standrad of Sichuan.