Preliminary Study On Syndrome Elements Of Colon Slow Transit Constipation

Objective:According to data concerning the four diagnostic methods for patients with colon slow transit constipation(STC),dialectical and statistical analysis of syndrome elements was conducted in the study to preliminarily explore rules of STC syndrome elements,to obtain rules of the syndrome elements,and to provide beneficial reference for clinical differentiation of STC.Method:STC patients were enrolled as the study object;a syndrome element differentiation table was applied for collection of standard and comprehensive data concerning the four diagnostic methods.Collected data was summarized and analyzed with syndrome element differentiation method,statistical methods and integration of clinical conditions.Result:(1)A total of 92 patients with colon STC were enrolled in the study,including 36 males and 56 females.With respect to age distribution,patients aged 70-80Yr,70-69Yr,and 50-59Yr,40-49Yr and 30-39Yr accounted for 29.3%,25%,19.6%,17.4%and 8.7%respectively.with respect to disease course,cases with a disease course of above 9 years accounted for 40.2%of the total cases,while cases with disease courses of 6-9 years,3-6 years and below 3 years accounted for 25%,23.9%and 10.9%respectively.(2)Distribution of colon STC syndrome elements was as follows.1)With respect to distribution of disease locations in the study,the large intestine cases accounted for 60.9%,while spleen,liver,and stomach cases accounted for 25.2%,8.7%and 5.2%respectively.2)For distribution of disease natures in the study,cases with deficiency of yin,deficiency of vital energy,deficiency of blood,and stagnation of circulation of vital energy accounted for 22.8%,18.5%,18.1%and 13.9%,while cases with deficiency of yang,body fluid deficiency,hot constitution,dry constitution and moist constitution accounted for 10.8%,15.8%,5.4%,3.9%and 0.8%of the total amount.(3)The distribution of colon STC syndrome element combination was as follow.1)Two-element cases(n=12)accounted for 13%,while three-element cases(n=23),four-element cases(n=23),five-element cases(n=15)and six-element cases accounted for 25%,25%,16.3%and 20.7%respectively.Distribution of different syndrome element combination was significantly different among different age groups(P<0.05)and significantly different among different disease course groups(P<0.05).2)With respect of nature of syndrome element natures in the study,cases with deficiency syndrome(n=38),excess syndrome(n=10)and deficiency-excess mixed syndrome(n=44)accounted for 41.3%,10.9%and 47.8%.The STC cases showed significant differences of the nature distribution;while distribution of different natures was significantly different among different age groups(P<0.05)and different disease course groups(P<0.05).The cases with combination of deficiency and excess syndrome elements showed significant gender difference(P<0.05).Conclusion:(1)In patients with colon STC,the amount of female patients is higher than male cases,while patients aged 70-80Yr account for the major part.(2)With respect to disease location of STC cases,large intestinal cases account for the major part,and others involve spleen,liver and stomach.For syndrome element of disease nature,deficiency of yin,deficiency of vital energy,deficiency of blood,and stagnation of circulation of vital energy account the major part.It involves element of disease nature,deficiency of yang,body fluid deficiency,hot constitution,dry constitution and moist constitution.(3)There are many syndrome element combination types in the STC cases,including four-element and three-element combinations,which account for the major part,and two-element,five-element and six-element combinations.It is indicated that the disease is caused by multiple factors,which show the diversification of element combinations.With the increase of age and course of disease,the number of combinations of syndrome elements increased.(4)With respect to STC syndrome element combination,cases with deficiency syndrome manifestation account for the top proportion,and followed by deficiency-excess mixed syndrome and excess syndrome in consequence.The deficiency-excess mixed syndrome cases rank the top in male cases,while the deficiency syndrome cases account for the top proportion in female cases.With the increase of age,Syndrome element combination shows a tendency toward deficiency syndrome manifestation with the increase of age,and a tendency toward both deficiency syndrome and deficiency-excess mixing syndrome manifestations with the extending of disease group.