Study Of Treating Of Senile Osteoporotic Vertebral Compression Fractures' Relationship Between The Injection Quantity Of Bone Cement And The Effect Of Pain Killer By PKP

Objective: To evaluate the treating of senile osteoporotic vertebral compression fractures' relationship between the injection quantity of bone cement and the effect of pain killer by PKP.Methods: Selected 90(140 vertebral bodies)cases' elderly patients with osteoporotic vertebral compression fractures during October 2015 to October 2016 and with a complete imaging data and conform to the vitreoretinal surgery of PKP as the research object,the patients' ages range of 65-65,involving the scope of T10-L3 vertebral bodies.All patients were divided into group A(small dose of bone cement 1 ~ 3 ml),20 patients(20 vertebral bodies);Group B(normal dose of bone cement 3 ~ 6 ml),65 patients(115 vertebral bodies);Group C(large dose of bone cement > 6 ml),5 patients(5 vertebral bodies)according to be given different bone cement dosage.To divide group A(at the injection site is located in the vertebral body on 1/3),10 patients(10 vertebral bodies);Group B(located in the center of the vertebral bodies),50 patients(100 vertebral bodies);Group C(in the vertebral body fracture line),30 patients(30 vertebral bodies)according to the injection site of bone cement.And to divide group A(bone cements do not through the middle line of the vertebral body),30 patients(65 vertebral bodies);Group B(through the middle line),60 patients(75 vertebral bodies)according to the degree of bone cements' dispersion observed from the postoperative X ray film of thoracolumbar.And 7 patients(10 vertebral bodies)appeared the leakage of bone cement.To observe and compare the preoperation,1 day after postoperation and 1 month after postoperation' VAS score.Results: All 90(140 vertebral bodies)patients' operations were successful and no serious complications occurred and 7 cases with bone cement leakage and no clinical symptoms and pain relief.There are no statistical difference to compare with the VAS score of Group A(small dose of bone cement 1 ~ 3 ml),group B(normal dose of bone cement 3 ~ 6 ml)and group C(large dose of bone cement> 6ml)in the point of 1 day after postoperation and 1 month after postoperation(P > 0.05).There has a significantly lower compare each group's VAS score in the point of 1 day after postoperation and 1 month after postoperation with preoperation and compare each group's VAS score in the point of 1 month after postoperation with 1 day after postoperation(P < 0.01).There are no statistical difference to compare with the VAS score of each group(group A(at the injection site is located in the vertebral body on 1/3),Group B(located in the center of the vertebral bodies),Group C(in the vertebral body fracture line))in the point of 1 day after postoperation and 1 month after postoperation(P > 0.05).There are no statistical difference to compare with the VAS score of each group(group A(bone cements do not through the middle line of the vertebral body),Group B(through the middle line))in the point of 1 day after postoperation and 1month after postoperation(P > 0.05).Conclusion: PKP has a significant effect to the pain caused by senile osteoporotic vertebral compression fracture and the recent analgesic effect is remarkable.But to inject different doses of bone cement has no obvious difference to the analgesic effect of patients.The different sites of inject bone cement and the degree of bone cement's dispersion has no significant effect to the analgesic effect.