Analysis On The Status And Influencing Factors Of Mother To Child Transmission Of HIV/AIDS In Xinjiang

ObjectiveTo understand the status and implementation of interventions from mother to child transmission of HIV/AIDS in Xinjiang,and to explore the influencing factors of mother to child transmission of HIV/AIDS,so as to provide policy basis for reducing the rate of mother to child transmission of HIV/AIDS in Xinjiang.MethodUsing the method of retrospective study,PMTCT monthly report,HIV-infected maternal and children's case card,follow-up card were collected,through the "prevention of AIDS,syphilis and hepatitis B mother to child transmission information management system" of Xinjiang 2010-201,which are distributed over 94 counties of 14 prefectures.We got distribution throughout Xinjiang maternal infection,infection of maternal social demographic characteristics,route of transmission and risk behavior,maternal care and delivery situation,the application of antiviral drugs and drug application among children,feeding method,test results and other information.We used the rate,composition ratio,chi-square test,trend test,Fisher exact test and logistic regression model to analyze the implementation of interventions and the influencing factors of mother to child transmission of HIV/AIDS in Xinjiang.Result1.2010-2015 reported HIV positive pregnant women 4007 cases in Xinjiang,maternal HIV detection positive rate was 0.15%.The positive rate of HIV was between 14% and 0.16%.2.Between 2010 and 2015,2,832 cases of HIV positive lying-in women were reported,with the age distribution mainly between 25 and 35 years old,accounting for 63.63 percent;Uygur accounted for 92.62%;the education level was mainly junior high school and primary school,accounting for 73.34%;the unemployed and farmers and herdsmen accounted for 87.89%;while the sexually transmitted HIV transmission was 61.62%.The rate of remarriage of infected mothers increased year by year(?2 =27.97,P=0.00),from 34.76% in 2010 to 46.38% in 2015.The number of pregnant women who delivered more than 3 times showed an upward trend(?2 =15.13,P=0.00),from 2.67% in 2010 to 8.07% in 2015.3.Between 2010 and 2015,the proportion of maternal infection in pregnant women was only 26.77% in the first 12 weeks of pregnancy.The rate of antiviral drug administration in maternal and children born in 2010-2015 increased year by year(?2= 15.73,P = 0.00,?2= 26.83,P = 0.00),they were 83.02% and 89.37% respectively in 2015.But only 42.60% pregnant women were given the drug 14 weeks ago.The artificial feeding rate of children infected with maternal was 94.23%.From 2010 to 2015,the cumulative rate of mother to child transmission of HIV/AIDS was 4.49%,and it was 4.78% in 2015.4.HIV mother to child transmission of the single factor analysis showed that the infected women's educational level,the delivery times,to accept PMTCT services time,the place of delivery,whether to take antiviral drugs and when to start taking medicine,whether the children born to take antiviral drugs,mother and child drug situation,feeding patterns could influence the rate of mother to child transmission,the difference was statistically significant(P<0.05).Multivariate regression model showed that the delivery times of infected women,the place of delivery,when to start taking medicine and whether to take medicine for their newborn babies were the factors that affect mother to child transmission of HIV/AIDS(P<0.05).ConclusionThe positive rate of HIV detection in pregnant women in Xinjiang was at a high level throughout the country(in 2014,the average positive rate of maternal HIV detection was 0.05%),and the mother to child transmission of HIV/AIDS epidemic situation was facing a serious situation.The majority of infected women were Uygur,the education level was generally low,most of them are housewives,and the proportion of remarriage and repeated pregnancy was higher,which increases the risk of mother to child transmission.The proportion of HIV detection and taking antiviral drugs in Xinjiang was still low in the early stages of pregnancy,to be further improved.The delivery times of infected women,the place of delivery,when to start taking medicine and whether to take medicine for their newborn babies were the factors that affect mother to child transmission of HIV/AIDS.We recommended to further strengthen the contraceptive counseling and guidance,to avoid unwanted pregnancy for women infected,to carry out health education activities effectively,advocating hospital delivery,improving the level of personnel in primary health care institutions,in order to ensure that infected pregnant women and children to get standardized intervention services as soon as possible,to reduce HIV infection in children.