The Research Of Ultrasound-guided Puncture Combined Surgical Resection For The Treatment Of Hepatic Alveolar Echinococcosis Which Has Central Cavity Fulled Of Necrotic Tissue

Objective:To explore the safety and effectiveness of ultrasound-guided puncture drainage combined with radical resection for hepatic alveolar echinococcosis which has central cavity fulled of necrotic tissue.Method:A retrospective analysis of seventeen patients with HAE which has central cavity fulled of necrotic tissue in Qinghai University Affiliated Hospital from January 2014 to August 2016 was performed.Among them,10 patients were treated with ultrasound-guided puncture drainage combined with resection(experience group),and 7 cases were treated with resection(control group).To analyze the operation time,the operative blood loss,the laboratory tests of preoperative and postoperative and complication between the 2 groups.And to observe the imaging changes before and after treatment.Result:1.The operation time of the experience group and control group is 308 ±23.00 min and 389 ± 95.70 min respectively,and the difference was statistically significant(P =0.026).The surgical bleeding of ultrasound-guided puncture drainagecombined with resection group and resection group is 360.00±182.87 ml and1607.14±205.00 ml,and the difference was statistically significant(P=0.019).2.The prothrombin time(PT)of the experience group and control group is 3.75± 0.89 s and 15.51 ± 1.72 s respectively,and the difference was statisticallysignificant(P =0.036).3.The alanine aminotransferase(ALT)of the experience group and controlgroup is 81.90±20.90 U/L and 108.14±29.45 U/L respectively,and the differencewas statistically significant(P =0.048).4.The differences of White blood cell,Hemoglobin,Transaminase and Albumin between before and after ultrasound-guided puncture drainage weren’t statistically significant(P >0.05).Conclusion:Ultrasound guided percutaneous drainage combined with surgical resection can shorten the operation time,reduce the amount of bleeding,accelerate the recovery of liver function after operation.Therefore,it is a safe and effective treatment.It has an important reference value for the treatment improved of hepatic alveolar echinococcosis which has central cavity fulled of necrotic tissue.