Autopsy Data Analysis Of 47 Cases Of Pulmonary Thromboembolism

objective:pulmonary thromboembolism(PTE)was a potential fatal disease.A lot of people only could be definite diagnosed by Autopsy.This article aimed to improve the understanding of the clinical and pathological characteristics of pulmonary thromboembolism.Methods : Autopsy and clinical data of the 47 autopsy-confirmed cases with PTE in the Chongqing Medical University from January 2004 to December 2015 were retrospectively analyzed.The content mainly included: the general situation,the underlying disease and risk factors,clinical manifestations,diagnose and pathological characteristics.Results : 1)A total of 784 autopsies were performed during the 12 years,of which 47 cases(6.0%)were proved as PTE and 46 cases were fatal pulmonary embolism(FPE).2)From these data we found that all cases had risk factors and 43 cases(91.3%)had two or more risk factors,and the most common risk factors were traumatic fracture(26 cases,55.3%)and surgeries(25 cases,53.2%).The most frequent symptoms were dyspnea(19cases,40.4%),cardiac arrest(15 cases,31.9%)and syncope(13cases,27.7%).In 24 cases(51.1%),the thrombus were found in the deepvenous system of lower limbs at the same time and 10 cases(21.3%)were found in the cor dextrum,1case(2.1%)in the basilar artery.Among these case,28 cases(59.6%)were located at pulmonary artery,and 20 cases(42.6%)were saddle pulmonary embolism.There were 22 cases(46.8%)suspected with PTE before death,but none was given anticoagulation or thrombolytic therapy.Only 1 cases had low molecular heparin to prevent thrombosis.Conclusion:PTE was more likely to occur in those who had high risk factors,especially traumatic fractures and surgeries.Both the misdiagnosis rate and mortality were high due to the variability of clinical manifestation related to PTE.The awareness about the diagnose and treatment of patient who was suspected PTE was lacking.