Interventional Treatments For The Complications Of Transplanted Renal Allografts

ObjectiveTo respectively analyzed the follow-up data of patients with renal transplantation complications prefered to interventional treatments and evaluate the safety and effectiveness of multiple interventional therapy for complications occurring after renal transplantation.MethodsFrom August 2011 to March 2016,the clinical data of 26 patients with complications after renal transplantation undergoing interventional therapy were reviewed.Vascular and nonvascular complications were treated with different interventional techniques,and the curative effects were analyzed.Patients’demographics and clinical data including general condition,the onset of complications,S.Cr level improvement,technical success,the recurrence rate,complications after procedure and long-term outcomes were retrospectively analyzed and compared between vascular and nonvascular group.The quantitative and qualitative variables were compared using the Student’s t-test and Fisher exact probability method,respectively.ResultsAll procedures were successfully performed for the 26 patients,including 19 cases with vascular complications and 7 cases of non-vascular complications.The technical success rate of interventional therapy was 100%.After the procedure,the total creatinine level(SCr)was significantly improved,which decreased from preoperative(372.7±295.5)μmol/L to postoperative(184.3±138.4)μmol/L(P<0.001).No severe complications occurred.Further analysis indicated that no statistically significant differences in patient’s general condition,kidney donor source,anastomosis method existed between vascular intervention group and nonvascular intervention(P>0.05).However,the onset time of vascular complications was markedly earlier than that of nonvascular complications(1.8±1.4 months vs.118.3±54.4 months),the difference was statistically significant(P<0.001).During the follow-up period,interventional therapy had to be carried out in 2 patients and their creatinine level returned to normal after treatment,and transplanted renal artery embolization had to be performed in the other patient as whose pseudoaneurysm became enlarged.Therefore,25 of 26 allografts were saved with this minimally invasive salvage therapy.ConclusionsInterventional therapy is a safe,effective,and noninvasive method in treating complications for renal allograft and saving the transplanted kidney.